33 results
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Mycoplasma pneumoniae infection ... spherocytosis) • Infections ... #Hemolytic #Intravascular ... #Causes #differential ... #diagnosis #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
 -
and Intravascular ... Hemolysis - Differential ... circulation - Infections ... Differential #Diagnosis ... Algorithm #Causes #Hematology
Hemolytic Anemias - Differential Diagnosis Algorithm

Signs of anemia and hemolysis:
 • ↓ Haptoglobin
 • ↑ LDH
Hemolytic Anemias ... - Differential ... Hypersplenism, Infection ... #Anemias #Differential ... Diagnosis #Algorithm #hematology
Causes of Leukocytosis and Leukopenia - Differential Diagnosis
 • Eosinophilia (AEC > 500, hypereosinophilia > 1500):
and Leukopenia - Differential ... Neoplastic • Neutropenia ... Benign ethnic neutropenia ... Leukocytosis #Leukopenia #Differential ... Diagnosis #causes #hematology
Isolated Neutropenia - Differential Diagnosis Algorithm
Chronic (>3 months):
 • Extrinsic: Vitamins
 • Intrinsic: Congenital, Inflammatory
Transient:
 •
Isolated Neutropenia ... - Differential ... , Non-infectious ... #Differential # ... Diagnosis #Algorithm #hematology
Differential Diagnosis for Hemolytic Anemia
Intrinsic Causes:
 • Enzyme deficiencies ex. G6PD, pyruvate kinase 
 • Hemoglobinopathies
Differential Diagnosis ... for Hemolytic Anemia ... drug induced • Infections ... IVIG infusion Intravascular ... classification #hematology
Causes of Hemolytic Anemia - Differential Diagnosis
Inherited
 • Membrane
 • Internal
    - Hemoglobin
Causes of Hemolytic ... Anemia - Differential ... Internal - Infectious ... #Anemia #Differential ... Diagnosis #Causes #hematology
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm
Sequestration:
 • Splenomegaly
Marrow Infiltration:
 • Hematologic and non-hematologic
Causes of Neutropenia ... Pancytopenia - Differential ... malignancies • Infection ... #Differential # ... Algorithm #Causes #Hematology
Iron Deficiency Anemia - Differential Diagnosis Algorithm

Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR

 • Blood loss:
Deficiency Anemia - Differential ... • Iron loss: Intravascular ... ) hemolysis, Intensive ... Deficiency #Anemia #Differential ... Algorithm #ferritin #hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
- Due to Viral infection ... Diagnosis: • hemolytic ... younger pts) Differential ... the RBCs causing intravascular ... #anemia #hematology