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diagnosis differential infectiousdiseases management infections clinical endocarditis microbiology microscopy treatment infective lung msk negative physicalexam abscess adrenal brain cardiology concurrent
Endemic Mycoses Summary • Blastomyces dermatitidis • Histoplasma capsulatum • Coccidioides immitis/posadasii • Paracoccidioides brasiliensis by Tim
Endemic Mycoses ... uw_IMresidency #Mycoses ... #fungi #infections ... #diagnosis #fungal
Important Fungal Stains Mycology Lab: • Calcofluor white - Fluorochrome that binds glucans and chitin in fungal
Important Fungal ... preparation from culture ... cell response to fungi ... doesn't stain most fungi ... staining #diagnosis #fungi
Causes of Culture Negative Abscess - Differential Diagnosis Framework Consider prior antibiotics as a cause of a
Causes of Culture ... antibiotics as a cause ... of a negative culture ... Scedosporium, endemic fungi ... Kumfer @AnnKumfer #Culture
1,3 Beta-D-Glucan and Galactomannan - Pathogens, and Testing Characteristics 1,3 ß-D-glucan: • Most fungi excluding mucor and
ß-D-glucan: • Most fungi ... Glucan-containing gauzes ... inconsistently in other fungi ... InfectiousDiseases #Diagnosis #Fungus ... #Fungi #Fungal
Microorganisms Responsible for Infective Endocarditis Native valves: - Streptococcus viridans - Enterococci - Other streptococci
Gram-negative bacilli - Fungi ... Histoplasma) - Culture ... Gram-negative bacilli - Fungi ... streptococci - Culture
Causes of blood culture negative infective endocarditis Bartonella spp, Brucella spp, Coxiella burnetii, Chlamydia spp, Tropheryma whipplei,
Causes of blood ... culture negative ... Tropheryma whipplei, Fungi ... identified with modern culture ... #culture #negative
Endocarditis Algorithm - Infective vs Noninfective Causes Noninfective: • Malignancy • Autoimmune disease • Systemic infection Native Valve
vs Noninfective Causes ... • HACEK • Culture-negative ... Gram-negative bacilli • Fungi ... Gram-negative bacilli • Fungi ... #Noninfective #Causes
Blood Culture-Negative Infective Endocarditis (BCNIE) Definition: No etiology found after 3 separate blood cultures remain negative for
Blood Culture-Negative ... fastidious bacteria or fungi ... but important causes ... Tropheryma whipplei, Fungi ... bacteria) and 18S ( fungi
Septic Arthritis: Pathogenesis and clinical findings Notes: - Septic Arthritis is typically monoarticular & the knee is involved
involved in >50% of cases ... & often a +ve culture ... S.A. can also be caused ... by, fungi, viruses
My Patient with Infective Endocarditis (IE) Has Negative Blood Cultures - Did they receive antibiotics prior
Negative Blood Cultures ... antibiotics prior to cultures ... therapy - Number one cause ... of culture negative ... Fungal (Histoplasma
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