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differential hepatology injury liver workup causes hemolysis hemolytic hepatitis pancytopenia acute agglutinin cold disease extravascular gap globulin hepatocellular intravascular lfts
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
Algorithmic Approach ... Diagnosis Framework ... PK, HbC, HbSS, PNH ... - Extrinsic: Autoimmune ... #hematology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Membrane): - Autoimmune ... Liver Disease, PNH ... Defects: Sickle cell anemia ... Laboratory Tests ... #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
- Differential Diagnosis ... Cold AIHA • PCH ... • PNH ... immune-complex hemolytic anemia ... #Hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Algorithm Consumption ... Autoimmune Mediated ... PNH 2. ... Acquired Aplastic Anemia ... #Algorithm #Hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Algorithm Consumption ... Autoimmune Mediated ... PNH 2. ... Acquired Aplastic Anemia ... #Algorithm #Hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Viral infection, autoimmune ... - Mycoplasma, EBV ... CLL (older) • Autoimmune ... test #cold # ... #hematology #diagnosis
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential Diagnosis ... Algorithm • Sickle ... elliptocytosis, autoimmune ... #hematology #testing
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
- Differential Diagnosis ... C, A, E, B, D, EBV ... Other: NAFLD, Autoimmune ... Causes #Acute #algorithm ... #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential Diagnosis ... Algorithm Vascular ... HBV, HCV, HEV, EBV ... extrahepatic source - Tests ... #algorithm #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
- Differential Diagnosis ... Injury → liver test ... Hepatitis A/B/C/D/E, EBV ... Other: NAFLD, Autoimmune ... #hepatology #algorithm
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