13 results
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
Disease Associations ANA ... - Drug-induced SLE ... Anti-mitochondrial (AMA ... polyangiitis U1-RNP ... diseases #diagnosis #table
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Rheumatology • Lupus (SLE ... ): ANA (anti-nuclear ... (SSB), others (RNP ... MCTD: Anti-UI RNP ... #associations #table
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
searched for when ANA ... Association with both SLE ... lupus Anti-(U1)RNP ... #rheumatology #table ... #ANA
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Manifestations: - CRP ... Workup: - ANA ... Manifestations: - CRP ... Workup: - ANA ... #comparison #table
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Malar rash 40% - Fever ... involvement 3% SLE-Related ... Auto-Antibodies: - ANA ... 10% - Anti-(U1)RNP ... Lupusreference #SLE
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
weight loss, and fever ... to: Arthritis, Fever ... : Drug induced SLE ... SSA can rule in SLE ... papillomavirus #SLE
Evaluation of suspected incomplete Kawasaki Disease

1. AHA consensus recommendations
2. Infants ≤6 months old on day ≥7
AHA consensus recommendations ... old on day ≥7 of fever ... purposes of this algorithm ... within 10 d of fever ... and lab signs (CRP
Giant AAA on POCUS

Elderly pt with abd/back pain. Stable. Has pulsatile mass on exam spans 12
Giant AAA on POCUS ... Stable. ... answer (of course)-POCUS ... Never let giant ... #Giant #POCUS #
Preoperative Risk Evaluation

Major Pre-Op Questions:
1. Does the patient have any modifiable risk factors that could be
or family - Ever ... ASA class If ... event, follow ACC algorithm ... Stable patients ... and undergoing AAA
Possible Algorithm for Workup of Fever of Unknown Origin (FUO)
Tier 1 Workup:
 • CBC, comprehensive metabolic
Possible Algorithm ... for Workup of Fever ... • LDH, SPEP, ANA ... • +/- ESR, +/- CRP ... DrEricStrong #FUO #Algorithm