533 results
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
Depolarization: • Na ... leading to a rapid Na ... Repolarization: • Na ... MOA: Block fast Na ... categories based on Na
Volume Based Approach to Hyponatremia
Hypovolemic, Serum uric acid >4
 • Urine Na <20: Extra-renal losses
 •
acid >4 • Urine Na ... 20: Extra-renal losses ... • Urine Na >30 ... : Renal losses, ... acid >4 • Urine Na
Clarke's Test (Patellar Grind Test)

Indicates Patellofemoral dysfunction.
 - Patient with knee in extension. Push posterior on
of patella then ask ... @PTstep_ #Clarkes ... Grind #clinical #video ... Patellofemoral #msk
Antiarrhythmics - Vaughan Williams Classification:
CLASS 1 - Sodium Channel Blockers:
 • MOA: Block fast Na+ channels
Classification: CLASS ... MOA: Block fast Na ... categories based on Na ... duration: - CLASS ... receptors, and Ca & Na
Antiarrhythmics - Vaughan Williams Classification
Class I (Ia, Ib, Ic) - Na+ Channel Blockade
 • Slows depolarization
Classification Class ... (Ia, Ib, Ic) - Na ... Widens QRS complex Class ... prolongs PR interval Class ... Classification #Classes
Diuretics - Pharmacology

Thiazides diuretics:
 • Inhibit Na+ Cl- cotransporter in distal tubule
 • Chlorothiazide, Chlorthalidone, Indapamide,
diuretics: • Inhibit Na ... diuretics: • Inhibit Na ... diuretics: • Inhibit Na ... diuretics: • Promote Na ... loop #thiazide #classes
Class I Antiarrhythmics and their Key Pharmacologic Properties

Class IA = Quinidine, Procainamide, Disopyramide ("Quarter PounDer")
Class IB
Class I Antiarrhythmics ... Properties Class ... Mayo, Pickle") Class ... Block fast Na ... QRS on EKG • Na
Guide to Acute Kidney Injury (AKI)

What to ask/look for: 
 - HPI, PMH, full ROS
AKI) What to ask ... weights - Urine Na ... rhabdo/TLS) Causes ... Diagnosis #Algorithm #Causes
Causes of Hypokalemia - Differential Diagnosis Algorithm
Increased Loss 
 - Increased GI Loss
 - Increased Urinary
Causes of Hypokalemia ... Stimulation of Na ... Diagnosis #Algorithm #causes
Antiarrhythmics - Sodium Channel Blockers
Subclasses, Mechanisms, Indications, Side Effects
la - Quinidine, Procainamide
lb - Lidocaine, Mexiletine
Ic -
Channel #Blockers #ClassI ... #Na #cardiology