74 results
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Kidney Injury - AKI Workup ... differential, urine ... dipstick, urine ... Myeloma: serum / urine ... blood culture, urine
Causes Abnormal Urine Color - Differential Diagnosis
Turbid White Urine (Albinuria):
 • Chyluria, Filariasis, Schistosomiasis, Malignancy, Phosphaturia,
Causes Abnormal ... Urine Color - Differential ... * Green Urine: ... : • Purple Urine ... UTI caused by (Proteus
Metabolic Pathways of Purple Urine Bag Syndrome: Adopted from chart originally published in Purple Urine Bag
Pathways of Purple Urine ... published in Purple Urine ... commonly grown in the urine ... #Pathophysiology ... #PUBS #Purple #Urine
Purple Urine Bag Syndrome
Chronic, indwelling catheter + bacteriuria (Providencia, Klebsiella, E.coli*) + alkaline urine
Tryptophan → Indoxyl
Purple Urine Bag ... Syndrome Chronic ... E.coli*) + alkaline urine ... BrighamChiefs #Purple #Urine ... #PUBS #pathophysiology
Hematuria Workup and Diagnosis Algorithm
 • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
Hematuria Workup ... Symptoms of UTI, urine ... WBCs, or urine ... → Urine culture ... urology #blood #urine
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
Hematuria: Red/Dark urine ... 1ml blood/liter urine ... more RBC/HPF spun urine ... examination of urine ... RBC - Brown urine
Pathophysiology of Tumor Lysis Syndrome (TLS)
Tumor Cell Lysis
-> Release of DNA
 • Purines -> Hypoxanthine /
Pathophysiology ... of Tumor Lysis Syndrome ... Nephropathy (low urine ... nephropathy (high urine ... #TLS #Pathophysiology
Evaluation of Secondary Hypertension
 • Primary aldosteronism - PRA, PAC
 • Renal artery stenosis - Renal
fT4 • Cushing syndrome ... cortisol. 24-h urine ... Mineralocorticoid excess syndromes ... resistant #Evaluation #workup
Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Proteinuria (Negative urine ... • Fanconi's syndrome ... Proteinuria (Positive urine ... albuminuria) - Active urine ... Post-infectious GN - Bland urine
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
Nephritic vs Nephrotic Syndrome ... nephrotic/nephritic syndromes ... hematuria (RBC casts ... dysmorphic RBCs in urine ... Nephritic #Nephrotic #Syndrome