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diagnosis management algorithm clinical lymphadenopathy mri msk radiology classification diffuse localized syndrome abscess aflp anemia apml arthritis bursitis childhood differentiation
Causes of Diffuse and Localized Lymphadenopathy - Differential Diagnosis Algorithm • Reactive (Inflammatory / Infectious) •
Causes of Diffuse ... ) #Diffuse #Focal ... Lymphadenopathy #LAD ... #Differential # ... #Hematology #Oncology
Causes of Localized Lymphadenopathy - Differential Diagnosis Algorithm Cervical: - Anterior • Infection
Causes of Localized ... #Localized #Focal ... Lymphadenopathy #LAD ... #Differential # ... #Hematology #Oncology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... Lymphadenopathy - Differential ... Lymphadenopathy #LAD ... Diagnosis #Algorithm #Causes ... #Hematology #Oncology
Multiple Myeloma and Monoclonal Gammopathies C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN R
Renal disease - Cr ... • Clonal bone marrow ... ratio ≥100 • >1 focal ... MGUS #diagnosis #hematology ... #oncology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... Volume (MCV) - Differential ... Thalassemia • Lead ... Hemolysis • Marrow ... #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Platelet Disorders - Differential ... HCV testing - Lab ... candidate) - Bone marrow ... or if a primary hematologic ... #Workup #hematology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... , dyspnea, +/- CXR ... Lysis Syndrome: • Pathophysiology ... diagnosis #management #hematology
Childhood Immunization Schedule: Why we immunize • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
muscle spasms lead ... Polio Virus -> Fecal-oral ... invade URT & via hematologic ... CNS and hematologic ... peds #pediatrics #pathophysiology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
ATRA treatment Pathophysiology ... common • Imaging: CXR ... initiation • Differential ... diagnosis #management #hematology ... #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
activity • ↓ LAP ... -> AML: Blast crises ... manifestations, hypoxia, CXR ... #Leukemia #Hematology ... #Oncology #Diagnosis
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