20 results
Daptomycin  - Antibiotics Class Overview

Mechanism: Lipopeptide antibiotic – forms transmembrane channels and depolarizes cells.
Class Overview ... No gram negative ... skin/soft tissue infections ... MRSA bacteremia/endocarditis ... #Review #Overview
Aminoglycosides  - Antibiotics Class Overview

Gentamicin, Tobramycin, Amikacin, Streptomycin -30S inhibitor (all IV)
Spectrum: Extremely efficacious vs.
Aminoglycosides - Antibiotics ... Class Overview ... . aerobic Gram negatives ... effect (mainly in endocarditis ... #Review #Overview
Carbapenems - Antibiotics Class Overview

Imipenem/Cilastin, Meropenem, Ertapenem, Doripenem 

Spectrum: Broadest spectrum antibiotics, cover Gram positive, Gram
Carbapenems - Antibiotics ... Class Overview ... positive, Gram negative ... resistant gram negatives ... #Review #Overview
Infective endocarditis - etiology and sources of infection. 
 • Native and prosthetic 
valve endocarditis
 •
Infective endocarditis ... and sources of infection ... • Native and ... • Soft tissue infections ... for TPN) and antibiotic
Tigecycline (IV) - Antibiotics Class Overview

Mechanism: Glycylcycline class - structurally related to Tetracyclines (bacteriostatic).  Only
Tigecycline (IV) - Antibiotics ... Class Overview ... and VRE), Gram negatives ... intraabdominal infections ... #Review #Overview
Vancomycin and Dalbavancin (lipoglycopeptide antibiotics) - Antibiotics Class Overview

Mechanism: Glycopeptide -  inhibits cell wall synthesis
lipoglycopeptide antibiotics ... ) - Antibiotics ... Class Overview ... No gram negative ... #Review #Overview
Flutycosine - Antibiotics Class Overview
 - 
Mechanism: 5-FC interferes with DNA and protein synthesis.  Only
Flutycosine - Antibiotics ... Class Overview ... (endocarditis, ... #Pharmacology #Antibiotics ... #Review #Overview
Coverage of common antibiotics used in the hospital

For empiric coverage, first define the type of infection,
Coverage of common antibiotics ... define the type of infection ... Consult ID if needed ... #management #infectiousdisease ... #antibiotics
Complications of Staph Aureus Bacteremia
 • CNS Infections
 • Septic pulmonary embolism (0.9% - 18.8%)
 •
Bacteremia • CNS Infections ... ) • Infective endocarditis ... - Native valve ... arthritis - Native ... joint (28-35%) ID
Blood Culture-Negative Infective Endocarditis (BCNIE)
Definition: No etiology found after 3 separate blood cultures remain negative for
Blood Culture-Negative ... Infective Endocarditis ... cultures remain negative ... #Infective #Endocarditis ... differential #workup #infectiousdiseases