21 results
Daptomycin  - Antibiotics Class Overview

Mechanism: Lipopeptide antibiotic – forms transmembrane channels and depolarizes cells.
Daptomycin - Antibiotics ... No gram negative ... skin/soft tissue infections ... MRSA bacteremia/endocarditis ... #Review #Overview
Aminoglycosides  - Antibiotics Class Overview

Gentamicin, Tobramycin, Amikacin, Streptomycin -30S inhibitor (all IV)
Spectrum: Extremely efficacious vs.
Aminoglycosides - Antibiotics ... . aerobic Gram negatives ... infections especially ... effect (mainly in endocarditis ... #Review #Overview
Carbapenems - Antibiotics Class Overview

Imipenem/Cilastin, Meropenem, Ertapenem, Doripenem 

Spectrum: Broadest spectrum antibiotics, cover Gram positive, Gram
Carbapenems - Antibiotics ... Broadest spectrum antibiotics ... positive, Gram negative ... resistant gram negatives ... #Review #Overview
Infective endocarditis - etiology and sources of infection. 
 • Native and prosthetic 
valve endocarditis
 •
Infective endocarditis ... and sources of infection ... • Native and ... • Soft tissue infections ... for TPN) and antibiotic
Coverage of common antibiotics used in the hospital

For empiric coverage, first define the type of infection,
define the type of infection ... , then review prior ... Consult ID if needed ... #management #infectiousdisease ... #antibiotics
Tigecycline (IV) - Antibiotics Class Overview

Mechanism: Glycylcycline class - structurally related to Tetracyclines (bacteriostatic).  Only
Tigecycline (IV) - Antibiotics ... and VRE), Gram negatives ... intraabdominal infections ... #Pharmacology #Antibiotics ... #Review #Overview
Vancomycin and Dalbavancin (lipoglycopeptide antibiotics) - Antibiotics Class Overview

Mechanism: Glycopeptide -  inhibits cell wall synthesis
lipoglycopeptide antibiotics ... ) - Antibiotics ... No gram negative ... gram positive infections ... #Review #Overview
Flutycosine - Antibiotics Class Overview
 - 
Mechanism: 5-FC interferes with DNA and protein synthesis.  Only
Flutycosine - Antibiotics ... severe fungal infections ... (endocarditis, ... #Pharmacology #Antibiotics ... #Review #Overview
Complications of Staph Aureus Bacteremia
 • CNS Infections
 • Septic pulmonary embolism (0.9% - 18.8%)
 •
Bacteremia • CNS Infections ... ) • Infective endocarditis ... - Native valve ... arthritis - Native ... joint (28-35%) ID
Blood Culture-Negative Infective Endocarditis (BCNIE)
Definition: No etiology found after 3 separate blood cultures remain negative for
Blood Culture-Negative ... Infective Endocarditis ... Work-up of BCNIE relies ... #Infective #Endocarditis ... differential #workup #infectiousdiseases