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diagnosis differential management endocarditis infective bcnie causes culture infections pathogens treatment abscess algorithm associated bacteria betadglucan bloodculture bloodcultures candidemia candidiasis
Microorganisms Responsible for Infective Endocarditis Native valves: - Streptococcus viridans - Enterococci - Other streptococci
bacilli - Fungi ... (Candida, Aspergillus ... ) - Culture negative ... bacilli - Fungi ... #Differential #InfectiousDiseases
1,3 Beta-D-Glucan and Galactomannan - Pathogens, and Testing Characteristics 1,3 ß-D-glucan: • Most fungi excluding mucor and
ß-D-glucan: • Most fungi ... Primarily studied for candida ... positives: Beta lactam antibiotics ... Specificity #Laboratory #InfectiousDiseases ... #Fungi #Fungal
My Patient with Infective Endocarditis (IE) Has Negative Blood Cultures - Did they receive antibiotics prior
Endocarditis (IE) Has Negative ... Did they receive antibiotics ... Decreased yield due to antibiotic ... Fungal (Histoplasma ... patient a surgical candidate
Causes of Culture Negative Abscess - Differential Diagnosis Framework Consider prior antibiotics as a cause of a
Causes of Culture Negative ... Consider prior antibiotics ... as a cause of a negative ... AnnKumfer #Culture #Negative ... Differential #Diagnosis #InfectiousDiseases
Transplant Infections Timeline Pre-transplant: • Common bacteria (endogenous): Staphylococci (skin), Gram-negative bacilli (gut) • Viruses: HSV (reactivation) Engraftment:
Staphylococci (skin), Gram-negative ... Staphylococci (skin), Gram-negative ... difficile (gut) • Fungi ... : Candida spp. ... diagnosis #causes #infectiousdiseases
Causes of blood culture negative infective endocarditis Bartonella spp, Brucella spp, Coxiella burnetii, Chlamydia spp, Tropheryma whipplei,
blood culture negative ... Tropheryma whipplei, Fungi ... (Aspergillus, Candida ... causes #culture #negative ... #Endocarditis #InfectiousDiseases
Candidemia Workup and Management - IDSA Guidelines 1) Antibiotics • Empiric: Echinocandins (e.g. micafungin) for most patients
Guidelines 1) Antibiotics ... Susceptibilities, Negative ... workup dictated by symptoms ... Guidelines #Management #candida ... candidiasis #treatment #fungal
CAPD-associated peritonitis (Continuous Ambulatory Peritoneal Dialysis) - 5 Things To Know Diagnosis (Two of the following): (1) Clinical
• 15-35% Gram negative ... peritonitis • Fungal ... prior abx use, fungal ... • Prophylactic antibiotics ... Diagnosis #Management #InfectiousDiseases
Blood Culture-Negative Infective Endocarditis (BCNIE) Definition: No etiology found after 3 separate blood cultures remain negative for
Blood Culture-Negative ... cultures remain negative ... fastidious bacteria or fungi ... (Aspergillus, Candida ... differential #workup #infectiousdiseases
Debridement and Management of Prosthetic Joint Infection (PJI) Duration of symptoms <3 weeks OR <30 days
PJI) Duration of symptoms ... DDIs/AEs) - Fungus ... expectancy, poor candidacy ... Initial 6-12wk antibiotic ... - >2 week antibiotic
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