27 results
Novel Antibiotics Against 
Resistant Gram-negative Bacteria 

- IDagram
@ID_agram

#Novel #Antibiotics #Resistant #GramNegative #Bacteria #Management #Resistance
Novel Antibiotics ... Against Resistant ... Gram-negative Bacteria ... ID_agram #Novel #Antibiotics ... #Resistant #GramNegative
Carbapenems - Antibiotics Class Overview

Imipenem/Cilastin, Meropenem, Ertapenem, Doripenem 

Spectrum: Broadest spectrum antibiotics, cover Gram positive, Gram
Class Overview ... positive, Gram negative ... infections due to resistant ... gram negatives, ... #Review #Overview
Table of Antibiotics for Highly Resistant Gram Negative Infections 

Ceftazidime, Cefepime, Piperacillin/ Tazobactam, Carbapenems, Aztreonam, Aminoglycosides
Table of Antibiotics ... for Highly Resistant ... Gram Negative Infections ... Medicine #Antibiotics ... #Resistant #GramNegative
Some Mechanisms of Resistance to Antibiotics
 • Drug resistance due to altered targets
to Antibiotics ... • Drug resistance ... ß-Lactams enter gram-negative ... penicillinases) destroy antibiotic ... #Antibiotic #Resistance
Daptomycin  - Antibiotics Class Overview

Mechanism: Lipopeptide antibiotic – forms transmembrane channels and depolarizes cells.
Daptomycin - Antibiotics ... Class Overview ... Mechanism: Lipopeptide antibiotic ... No gram negative ... #Review #Overview
Aminoglycosides  - Antibiotics Class Overview

Gentamicin, Tobramycin, Amikacin, Streptomycin -30S inhibitor (all IV)
Spectrum: Extremely efficacious vs.
Aminoglycosides - Antibiotics ... Class Overview ... . aerobic Gram negatives ... : serious gram negative ... #Review #Overview
Tigecycline (IV) - Antibiotics Class Overview

Mechanism: Glycylcycline class - structurally related to Tetracyclines (bacteriostatic).  Only
Tigecycline (IV) - Antibiotics ... Class Overview ... and VRE), Gram negatives ... #Pharmacology #Antibiotics ... #Review #Overview
SPICE (SPACE) Organisms
 - Colloquial acronym for gram-negative bacteria that have inducible, chromosomal beta-lactamase genes known
acronym for gram-negative ... - Resistance ... to beta-lactam antibiotics ... Organisms #AmpC #Resistance ... #Antibiotics
Antifungal Echinocandins  - Antibiotics Class Overview

Mechanism: Inhibit glucan synthesis in fungal cell wall by blocking
Echinocandins - Antibiotics ... Class Overview ... rare reports of resistance ... #Pharmacology #Antibiotics ... #Review #Overview
Vancomycin and Dalbavancin (lipoglycopeptide antibiotics) - Antibiotics Class Overview

Mechanism: Glycopeptide -  inhibits cell wall synthesis
lipoglycopeptide antibiotics ... ) - Antibiotics ... Class Overview ... No gram negative ... #Review #Overview