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diagnosis management cardiology infectiousdiseases overview review amikacin aminoglycosides antibiogram antibiotic bacteria candida candidemia candidiasis causes children culture daptomycin etiology failure
Daptomycin - Antibiotics Class Overview Mechanism: Lipopeptide antibiotic – forms transmembrane channels and depolarizes cells.
Daptomycin - Antibiotics ... No gram negative ... MRSA bacteremia/endocarditis ... cidal nature) #Pharmacology ... #Antibiotics #Review
Aminoglycosides - Antibiotics Class Overview Gentamicin, Tobramycin, Amikacin, Streptomycin -30S inhibitor (all IV) Spectrum: Extremely efficacious vs.
Aminoglycosides - Antibiotics ... . aerobic Gram negatives ... : serious gram negative ... effect (mainly in endocarditis ... #Pharmacology #Antibiotics
Infective endocarditis - etiology and sources of infection. • Native and prosthetic valve endocarditis •
Infective endocarditis ... • Native and ... prosthetic valve endocarditis ... for TPN) and antibiotic ... Bacteria #Etiology #Differential
Endocarditis Summary Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV substance use • IV catheter • Recent
• Coagulase-negative ... Marantic (NTBE) Differential ... • IV Antibiotics ... annular or aortic abscess ... Complications: Abscess
Causes of Culture Negative Abscess - Differential Diagnosis Framework Consider prior antibiotics as a cause of a
Causes of Culture Negative ... Abscess - Differential ... Consider prior antibiotics ... as a cause of a negative ... #Abscess #Differential
Fever Patterns - Differential Diagnosis Framework Continuous Fever: Temp > 38°C with only 1 degree fluctuation in 24
Fever Patterns - Differential ... • Typhus, gram-negative ... infection • Abscess ... • Hepatic abscess ... Fever #Patterns #Differential
Causes of Antibiotic Failure - Differential Diagnosis Framework Diagnosis: • Non-Infectious: Malignant, Autoimmune, Drug-related (NMS, serotonin syndrome,
Causes of Antibiotic ... Failure - Differential ... Source control (abscess ... lines, osteo, endocarditis ... #Failure #Differential
Candidemia Workup and Management - IDSA Guidelines 1) Antibiotics • Empiric: Echinocandins (e.g. micafungin) for most patients
Guidelines 1) Antibiotics ... Susceptibilities, Negative ... within one week to assess ... clinical concern for endocarditis
Endocarditis - Overview and Differential Diagnosis Framework Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV
and Differential ... aureus, Coagulase-negative ... staphylococci Culture Negative ... Treatment • IV antibiotics ... #Differential #
Intern Pocket Cards - Antibiogram and Susceptibilities VRE - MRSA - GRAM POSITIVES - GRAM NEGATIVES -
POSITIVES - GRAM NEGATIVES ... Confirm type of IV access ... Susceptibilities #antibiotics ... #management #pharmacology
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