59 results
Commonly Used Diagnostic Tests for Celiac Disease

Tissue transglutaminase (tTG) IgA antibodies
 - Most reliable noninvasive test
specificity - Falsely negative ... disease) - May be negative ... HLA-DQ8 - High negative ... Reflects response to treatment ... #Diagnosis #Workup
Gastrointestinal Evaluation of Iron Deficiency Anemia
In patients with anemia, diagnose iron deficiency if:
 • Ferritin <
chronic kidney tests ... Test for celiac ... endoscopy only if: • Negative ... change medical management ... Gastrointestinal #Evaluation #workup
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Diagnosis and Management ... • Immunologic Workup ... pANCA anti-MPO - Negative ... life-threatening • Treatment ... #Summary #rheumatology
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm

Suspected TMA: Unexplained thrombocytopenia + MAHA
Diagnosis and Management ... Direct antiglobulin test ... normal • DAT negative ... Differential #Diagnosis #Management ... #Algorithm #hematology
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
• Some false negative ... specific laboratory tests ... Disease #diagnosis #management ... #phenotypes #workup ... #treatment #rheumatology
Tetralogy of Fallot Summary
 • Anatomy
 • Incidence
 • Pathophysiology
 • Presentation
 • Common Variants
 •
• “Blue” Tet Options ... palliation • Post-Op Management ... Fallot #diagnosis #management ... #cardiology #peds ... #pediatrics #treatment
Approach to Gout
Diagnosis: r/o septic arthritis! Needle-shaped, negative birefringent crystals
Treatment:
 • Weight loss, diet, d/c culprit
Needle-shaped, negative ... Acute and chronic treatment ... gout #diagnosis #management ... #treatment #ULT ... #rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... antibody (ANA) test ... ANAs; thus, a negative ... Arthritis #laboratory #workup ... diagnosis #testing #Rheumatology
Diarrhea Workup and Management Algorithm in Transplant Patients
First Tier Microbiologic-Testing:
1. C. difficile PCR (Stool)
2. CMV qPCR
Diarrhea Workup ... and Management Algorithm ... Breath test for ... above testing negative ... #Diarrhea #Workup
Candidemia Workup and Management - IDSA Guidelines
1) Antibiotics
 • Empiric: Echinocandins (e.g. micafungin) for most patients
Candidemia Workup ... and Management ... Susceptibilities, Negative ... Additional metastatic workup ... #candidiasis #treatment