13 results
Tranexamic Acid - Indications and Pharmacology
Pharmacokinetics:
 • MOA: Inhibits plasminogen activation to plasmin & inhibits fibrinolysis
small amount of hepatic ... : Urine Common Uses ... rapid injection; Nausea ... events; Impaired color ... #Pharmacology #hematology
Portal venous gas on hepatic ultrasound: A concerning finding in the critically ill patient that should
venous gas on hepatic ... ultrasound: A concerning ... variety of other causes ... #hepatology #liver ... #pocus #clinical
Causes of Polycythemia (Erythrocytosis) - Differential Diagnosis Algorithm
Relative - Normal RBC Mass / Decreased Plasma Volume
Causes of Polycythemia ... Diagnosis Algorithm Relative ... Abnormal Abdominal Ultrasound ... Diagnosis #Algorithm #Causes ... #Hematology
Hepatic Metastases on POCUS 
Patient with history of colon cancer presents with right flank pain. Focused
on POCUS Patient ... with history of colon ... Focused renal u/ ... Note hepatic masses ... #clinical #ultrasound
Hepatic Metastases on POCUS 
Patient with history of colon cancer presents with right flank pain. Focused
on POCUS Patient ... with history of colon ... Focused renal u/ ... Note hepatic masses ... #clinical #ultrasound
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
dL the ULN R - Renal ... Causes of false- ... negative SPEP: ... amyloidosis Other causes ... MGUS #diagnosis #hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Bleeding (64%) • Renal ... Treat primary cause ... 100mg/dL) - Heparin ... Coagulation #diagnosis #causes ... treatment #management #hematology
Major Clinical Trials and Evidence Summary for Transfusion Thresholds in Critical Care

TRICC - NEJM 1999 -
NEJM 1999 - ICU FOCUS ... unnecessary and cause ... critically ill, septic ... Transfusion #Thresholds #Hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
decrease in most cases ... antiglobulin tests - Negative ... hematuria (without casts ... the presence of renal ... Diagnosis #Workup #Hematology
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
levels >1g/L • Negative ... cryoglobulins • Negative ... causes of secondary ... necrosis • DIC • Septic ... #hematology