45 results
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... Diagnosis and Management ... Positive in 60-80% of cases ... pANCA anti-MPO - Negative ... #Summary #rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Discontinuation of causal ... pANCA anti-MPO - Negative ... Usual therapeutic management ... comparison #table #rheumatology ... #diagnosis #management
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
pathophysiologic causes ... Post-strep GN, Lupus ... Pauci-immune mediated (Negative ... diagnosis #algorithm #rheumatology
Causes of Isolated Neutropenia - Differential Diagnosis Algorithm
Congenital
Medications
 • Anticonvulsants
 • Antibiotics
 • Antithyroid
 • Antihypertensive
Causes of Isolated ... Bacteria • Gram Negative ... Destruction • Systemic Lupus ... Diagnosis #Algorithm #Causes ... #Hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic Lupus ... autoantibodies that will cause ... Diagnosis of Lupus ... CNS #neurology #rheumatology ... cerebritis #diagnosis #management
Hydroxychloroquine Serum Measurement in SLE
 • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
suspected) • In case ... • Special cases ... Measurement #SLE #rheumatology ... pharmacology #levels #lupus ... #management
Hypotension - Rapid Response Management

1) Ask for vitals en route
2) Immediate Assessment
3) Examine for a cause:
Rapid Response Management ... 1) Ask for vitals ... Examine for a cause ... #Hypotension #Management ... #criticalcare #
Hypoxemia and Dyspnea - Rapid Response Management

1) Ask for vitals en route
2) Stabilize: Nasal canula 
3)
Rapid Response Management ... 1) Ask for vitals ... the underlying cause ... Hypoxemia #Dyspnea #Management ... #criticalcare #
Difficult Airway Algorithm

1. Assess the likelihood and clinical impact of basic management problems: 
 • Difficulty
impact of basic management ... • Difficult mask ... Consider the relative ... Anesthesiology #Anesthesia #CriticalCare ... #Management
Hemorrhagic Pericardial Effusions (Hemopericardium)- Differential Diagnosis Framework

IATROGENIC DISEASE
Secondary to invasive cardiac procedures

NONIATROGENIC
• Malignancy (e.g., metastatic spread:
OTHER RARE CAUSES ... induced • MCTD, Lupus ... may have false negative ... Differential #Diagnosis #cardiology