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diagnosis differential hematology algorithm criticalcare treatment checklist anesthesia anesthesiology cardiology intraoperative sle syndrome clinical dermatology pharmacology pocus pulmonary arthritis blood
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... • Immunologic Workup ... Positive in 60-80% of cases ... pANCA anti-MPO - Negative ... #Summary #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... Discontinuation of causal ... • Immunologic Workup ... pANCA anti-MPO - Negative ... comparison #table #rheumatology
Algorithm for the Evaluation and Management of Sickle Cell Crises Clinical Manifestations and Management #Diagnosis #Management #Hematology #SickleCell
Evaluation and Management ... of Sickle Cell Crises ... #Diagnosis #Management ... #Hematology #SickleCell ... Manifestations #Workup
Hydroxychloroquine Serum Measurement in SLE • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
[HCQI reflects long-term ... • Special cases ... Measurement #SLE #rheumatology ... pharmacology #levels #lupus ... #management
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
pathophysiologic causes ... Post-strep GN, Lupus ... Pauci-immune mediated (Negative ... diagnosis #algorithm #rheumatology
Causes of Isolated Neutropenia - Differential Diagnosis Algorithm Congenital Medications • Anticonvulsants • Antibiotics • Antithyroid • Antihypertensive
Causes of Isolated ... Bacteria • Gram Negative ... Destruction • Systemic Lupus ... Diagnosis #Algorithm #Causes ... #Hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic Lupus ... autoantibodies that will cause ... Diagnosis of Lupus ... CNS #neurology #rheumatology ... cerebritis #diagnosis #management
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
biliary, renal, lung ... • Some false negative ... Disease #diagnosis #management ... #phenotypes #workup ... #treatment #rheumatology
Cardiac Tamponade - Guidelines for Crises in Anaesthesia Caused by an accumulation of blood, pus, effusion fluid
or iatrogenic causes ... Plan definitive management ... of underlying cause ... Checklist #Diagnosis #Management ... #Workup
Hemorrhagic Pericardial Effusions (Hemopericardium)- Differential Diagnosis Framework IATROGENIC DISEASE Secondary to invasive cardiac procedures NONIATROGENIC • Malignancy (e.g., metastatic spread:
metastatic spread: lung ... OTHER RARE CAUSES ... induced • MCTD, Lupus ... may have false negative
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