28 results
Approach to Hypoproliferative Macrocytic Anemia

 • 812, Folate Deficiency
 • MDS+
 • Hypothyroid
 • Liver Disease
Hypothyroid • Liver Disease ... • Alcohol • ... #Macrocytic #Anemia ... differential #diagnosis #algorithm ... #hematology #workup
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Myelodysplastic syndrome ... tumors, Acute alcoholism ... Acanthocytes - Alcohol ... Hemolytic uremic syndrome ... #differential #hematology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
Algorithmic Approach ... Non-megaloblastic: Liver disease ... , Alcoholism, Hypothyroidism ... #MCV #Algorithm ... Differential #Diagnosis #hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV)
Low MCV - <80fL - "Microcytic"
 • Iron deficiency
chronic kidney disease ... use, Liver disease ... independent of alcohol ... Myelodysplastic syndrome ... diagnosis #causes #hematology
Iron Deficiency Anemia - Differential Diagnosis Algorithm

Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR

 • Blood loss:
Iron Deficiency Anemia ... Gastrectomy, WHDA syndrome ... Structural: Celiac disease ... Low iron diet, Alcoholism ... #ferritin #hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
HLH syndrome 5. ... Alcoholism Bone ... Acquired Aplastic Anemia ... Metastatic Disease ... #Hematology
Pancytopenia - Differential Diagnosis

Congenital Diseases:
• GATA2 deficiency
• Fanconi’s anemia
• Wiskott-Aldrich syndrome
• Ribosomopathy or telomeropathy

Cancer:
• Leukemia
• Lymphoma

Inflammatory
Congenital Diseases ... deficiency • Fanconi’s anemia ... Wiskott-Aldrich syndrome ... Deficiencies: • Alcohol ... Differential #Diagnosis #Hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
HLH syndrome 5 ... Alcoholism Bone ... Acquired Aplastic Anemia ... Metastatic Disease ... #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... hemolysis, deficiency anemia ... Vasculitides, IBD, Celiac disease ... Kawasaki, Nephrotic syndrome ... #hematology
Hepatomegaly - Differential Diagnosis Algorithm
Malignant
 • Primary Carcinoma
 • Metastases
 • Lymphoma
 • Leukemia
 • Polycythemia
Differential Diagnosis Algorithm ... Hemochromatosis • Wilson's Disease ... • Budd-Chiari Syndrome ... Inflammatory • Alcoholic ... #Causes #Hepatology