31 results
Autoimmune Hemolytic Anemia (AIHA) Pathophysiology - Warm vs Cold AIHA
Warm AIHA:
 - 70%; IgG mediated
 -
Autoimmune Hemolytic Anemia ... C3 positive or negative ... mediated - DAT: IgG negative ... Pathophysiology #diagnosis ... #hematology
Autoimmune Hemolytic Anemia (AIHA) - Differential Diagnosis Table

Warm AIHA (48-70%)
Cold AHA (16-32%)
 • Donath-Landsteiner HA (paroxysmal
Autoimmune Hemolytic Anemia ... - Differential Diagnosis ... AIHA (7-8%) DAT-negative ... #Differential #Diagnosis ... #Table #hematology
Approach to Gout
Diagnosis: r/o septic arthritis! Needle-shaped, negative birefringent crystals
Treatment:
 • Weight loss, diet, d/c culprit
Approach to Gout ... Diagnosis: r/o ... Needle-shaped, negative ... #diagnosis #management ... treatment #ULT #rheumatology
Warm vs Cold Autoimmune Hemolytic Anemia
Warm Autoimmune Hemolytic Anemia:
 • Mechanism: IgG and Complement-mediated
 • Etiology:
Autoimmune Hemolytic Anemia ... Autoimmune Hemolytic Anemia ... Autoimmune Hemolytic Anemia ... #hematology #diagnosis ... #comparison
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... - Differential Diagnosis ... Tests • Rule out ... #Differential #Diagnosis ... Algorithm #Causes #Hematology
Syphilis - Diagnosis and Management - Primary vs Secondary vs Tertiary
Primary Syphilis
 • Localized lymphadenopathy
 •
Syphilis - Diagnosis ... 30-40%) - Negative ... treponemal tests rule out ... Secondary #Tertiary #Comparison ... #Diagnosis #Management
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
result in severe anemia ... antiglobulin tests - Negative ... , ruling out an ... immune hemolytic anemia ... #Workup #Hematology
CPPD vs Gout

== CPPD == 

Think About CPPD When:
 • Self-limited synovitis after surgery/trauma (> 65
culture used to diagnose ... Needle-shaped, negatively ... stain and culture- Diagnose ... #Comparison #rheumatology ... #Diagnosis
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
Differential Diagnosis ... counts may delay diagnosis ... likelihood of negative ... #differential #diagnosis ... neutrophil #WBC #CBC #hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
• Symptoms of anemia ... anemia • Cold ... for anti-C3d and negative ... disease #hemolytic #anemia ... #hematology #diagnosis