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differential hemolytic aiha cold pathophysiology abdominal afib agglutinin anticoagulation bandemia bleed blood caput cbc chads2 chads2vasc direction disease flow gammopathies
Autoimmune Hemolytic Anemia (AIHA) Pathophysiology - Warm vs Cold AIHA Warm AIHA: - 70%; IgG mediated -
Autoimmune Hemolytic ... C3 positive or negative ... #Hemolytic #Anemia ... Pathophysiology #diagnosis ... #hematology
Autoimmune Hemolytic Anemia (AIHA) - Differential Diagnosis Table Warm AIHA (48-70%) Cold AHA (16-32%) • Donath-Landsteiner HA (paroxysmal
Autoimmune Hemolytic ... Anemia (AIHA) - ... Differential Diagnosis ... AIHA (7-8%) DAT-negative ... #Table #hematology
Warm vs Cold Autoimmune Hemolytic Anemia Warm Autoimmune Hemolytic Anemia: • Mechanism: IgG and Complement-mediated • Etiology:
Hemolytic Anemia ... Hemolytic Anemia ... Hemolytic Anemia ... #hematology #diagnosis ... #comparison
CHA2DS2VASc vs HAS-BLED scores for stroke risk and bleed risk on anticoagulation C Congestive Heart Failure 1 H Hypertension 1 A2 Age >75 2 D Diabetes Mellitus 1 S2 Stroke,
dL) 1 Liver (cirrhosis ... Bleeding history/anemia ... CHADS2VASc #HASBLED #Comparison ... Anticoagulation #AFib #Diagnosis ... #Hematology
Causes of Anemia in Cirrhosis - Differential Diagnosis Framework LOW RETIC INDEX - ↓ PRODUCTION • Vitamin
in Cirrhosis - ... Differential Diagnosis ... , Autoimmune hemolytic ... #Cirrhosis #Differential ... #Diagnosis #Hepatology
Multiple Myeloma and Monoclonal Gammopathies C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN R
40 ml/min A - Anemia ... Causes of false- negative ... macroglobulinemia, and autoimmune ... Gammopathies #MGUS #diagnosis ... #hematology #oncology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Viral infection, autoimmune ... anemia • Cold ... for anti-C3d and negative ... CLL (older) • Autoimmune ... #hematology #diagnosis
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Differential Diagnosis ... Corticosteroid use • Autoimmune ... likelihood of negative ... #differential #diagnosis ... neutrophil #WBC #CBC #hematology
Dilated Abdominal Veins and Caput Medusae - Direction of Blood Flow Vein Milking technique can be used
#Blood #Flow #physicalexam ... #diagnosis #hepatology ... #cirrhosis #obstruction ... #comparison #abdominal
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Liver disease: Cirrhosis ... , ETOH, autoimmune ... gastric tumors • Hematology ... #differential #diagnosis ... #hematology
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