9 results
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
NPSLE rare, Malar rash ... Workup: - ANA ... of autoantibodies ... Workup: - ANA ... pANCA anti-MPO - Negative
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
69% - Malar rash ... Auto-Antibodies: - ANA ... Diagnosis and Lupus ... Erythematosus #Diagnosis #autoantibodies ... #rheumatology
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
searched for when ANA ... Negative association ... #Antinuclear #autoantibodies ... erythematosus #diagnosis #rheumatology ... #table #ANA
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... Manifestations: Malar rash ... , oral ulcers, Lupus ... pANCA anti-MPO - Negative ... Management #Summary #rheumatology
Fluid-filled Rash - Diagnostic Algorithm.  Pustule: 1) Pustules more commonly suggest an infectious process (bacterial,
Fluid-filled Rash ... ) Often due to autoantibodies ... #Diagnosis #Dermatology ... Bullous #Algorithm #Differential ... #Ddxof
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... findings (ANA, ... • Anti-Ro/SSA autoantibodies ... permanent alopecia Differential ... vein thrombosis Hematologic
Top 10 situations when to think about lupus
1) Inflammatory joint pain (especially in the wrists and
everywhere) 2) A rash ... the face (many differential ... annular rash on ... children (pediatric SLE ... #diagnosis #sle
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential ... mucositis - Rash ... such as systemic lupus ... LFT • ESR • ANA ... SLE) • Urinalysis
Drug Induced Lupus (DIL)
 • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
Drug Induced Lupus ... NPSLE rare, Malar rash ... is rare in DIL, SCLE-DIL ... of autoantibodies ... #DIL #rheumatology