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diagnosis rheumatology erythematosus arthritis msk pain systemic comparison management monoarthritis monoarticular polyarthritis polyarticular vasculitis workup algorithm approach arthropathies arthropathy autoantibodies
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Associated with Joint ... Pain Rash ... infection Malar rash ... lesions • Discoid lupus ... #rashes #differential
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... Manifestations: Malar rash ... , oral ulcers, Lupus ... pANCA anti-MPO - Negative ... Management #Summary #rheumatology
Joint Disorders - Differential Diagnosis Algorithm Monoarthritis • Septic • Crystalline - Gout
- Differential Diagnosis ... of Lumbar Spine and ... with Systemic Lupus ... Erythematosus (SLE ... like “butterfly rash
Top 10 situations when to think about lupus 1) Inflammatory joint pain (especially in the wrists and
) Inflammatory joint ... everywhere) 2) A rash ... the face (many differential ... annular rash on ... #diagnosis #sle
Myositis and Myopathies Polymyositis • Progressive, symmetric muscle weakness • Elevated CK, +Anti-Jo, +Anti-Mi2 Dermatomyositis
muscle weakness, rash ... Anti-retrovirals, Gemcitabine Lupus ... • +ANA, +Anti-Smith ... uncommon 5-15% of lupus ... Myopathies #myopathy #differential
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
NPSLE rare, Malar rash ... Manifestations: Malar rash ... Workup: - ANA ... pANCA anti-MPO - Negative ... #table #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... permanent alopecia Differential ... Malignancy (e.g. hematologic ... Arthritis: • Joint ... arthropathy • 90% joints
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
69% - Malar rash ... Auto-Antibodies: - ANA ... Diagnosis and Lupus ... Lupusreference #SLE ... #rheumatology
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
spondyloarthropathies, lupus ... Chronic = RA, SLE ... remember yellow and ... #rheumatology # ... approach #workup #differential
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... of the affected joint ... • Systemic lupus ... , a negative ANA ... • Sacroiliac joint
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