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diagnosis rheumatology erythematosus arthritis dermatology joint management systemic algorithm comparison msk vasculitis workup activation antibodies antinuclear aortitis approach autoantibodies causes
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Rash • Human ... infection Malar rash ... • SLE • Human ... lesions • Discoid lupus ... #rashes #differential
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... Manifestations: Malar rash ... Workup: - ANA ... pANCA anti-MPO - Negative ... Management #Summary #rheumatology
Top 10 situations when to think about lupus 1) Inflammatory joint pain (especially in the wrists and
Inflammatory joint pain ... fingers, or pain ... everywhere) 2) A rash ... the face (many differential ... annular rash on
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
NPSLE rare, Malar rash ... Manifestations: Malar rash ... pANCA anti-MPO - Negative ... #sle #comparison ... #table #rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
69% - Malar rash ... Auto-Antibodies: - ANA ... Diagnosis and Lupus ... Lupusreference #SLE ... #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... findings (ANA, ... permanent alopecia Differential ... Malignancy (e.g. hematologic ... Arthritis: • Joint pain
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
assay (IFA) is the main ... erythematosus (SLE ... (SLE), Systemic ... #patterns #rheumatology ... #diagnosis #differential
Myositis and Myopathies Polymyositis • Progressive, symmetric muscle weakness • Elevated CK, +Anti-Jo, +Anti-Mi2 Dermatomyositis
muscle weakness, rash ... Rheumatica • Pain ... Diffuse muscle pain ... uncommon 5-15% of lupus ... Myopathies #myopathy #differential
Maculopapular - Diagnostic Algorithm Pathophysiology: - Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
sulfa-drug - Skin pain ... #Diagnosis #Dermatology ... #Rash #Maculopapular ... Targetoid #Algorithm #Differential ... #Ddxof
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
- Differential ... lesions • Severe pain ... Autoimmune Vasculitis (lupus ... for hepatitis B and ... #Differential #
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