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diagnosis rheumatology treatment differential lupus algorithm cardiology clinical dermatology endocarditis foamed icu pharmacology summary syndrome blood checklist comparison druginduced ecmo
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Diagnosis and Management ... Positive in 60-80% of cases ... pANCA anti-MPO - Negative ... Usual therapeutic management ... #Summary #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Discontinuation of causal ... pANCA anti-MPO - Negative ... Usual therapeutic management ... comparison #table #rheumatology ... #diagnosis #management
Hydroxychloroquine Serum Measurement in SLE • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
Measurement in SLE ... • Special cases ... #Measurement #SLE ... #rheumatology # ... levels #lupus #management
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... Disease, PRES Pathophysiology ... autoantibodies that will cause ... Erythematosus #SLE ... cerebritis #diagnosis #management
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
three primary pathophysiologic ... causes differentiated ... Pauci-immune mediated (Negative ... diagnosis #algorithm #rheumatology
Pain, Agitation, and Delirium (PAD) in the ICU Addressing the ICU Triad (PAD) can be accomplished through
it should not cause ... dissociative drug, it causes ... 0.5mg x1) for nausea ... Delirium #PAD #ICU #CriticalCare ... #diagnosis #management
Capnocytophaga Pathogen: Capnocytophaga • 9 species, C. canimorsus responsible for the majority of infections • Gram-negative rod,
infections • Gram-negative ... ), Malignancy, SLE ... fusiform gram-negative ... microbiology #zoonotic #infectiousdiseases ... #diagnosis #management
Global Alliance algorithm to improve outcomes in acne. †With small nodules (>0.5–1 cm). ‡Consider physical removal of comedones. §Second
Second course in case ... For pregnancy, see ... ††See text. alt. ... #Management #Dermatology
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... = nonspecific (nausea ... Liver #Pregnancy #hepatology ... obgyn #diagnosis #management ... #pathophysiology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... Autoimmune diseases: SLE ... Drugs, Unknown cause ... Lymphohistiocytosis #diagnosis #management ... treatment #summary #rheumatology
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