50 results
HACEK is the acronym commonly used to describe and help doctors to remember a group of
fastidious Gram-negative ... which can also cause ... is caused by HACEK ... is caused by Alpha-haemolytic ... #Diagnosis #InfectiousDiseases
Causes of blood culture negative infective endocarditis

Bartonella spp, Brucella spp, Coxiella burnetii, Chlamydia spp, Tropheryma whipplei,
culture negative ... infective endocarditis ... #culture #negative ... #Endocarditis # ... InfectiousDiseases
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
three primary pathophysiologic ... causes differentiated ... Cryoglobulinemia, Endocarditis ... Pauci-immune mediated (Negative ... diagnosis #algorithm #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Diagnosis and Management ... Positive in 60-80% of cases ... pANCA anti-MPO - Negative ... Usual therapeutic management ... #Summary #rheumatology
My Patient with Infective Endocarditis (IE) Has Negative Blood Cultures
 - Did they receive antibiotics prior
with Infective Endocarditis ... (IE) Has Negative ... therapy - Number one cause ... #Infective #Endocarditis ... #Diagnosis #Management
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Splenomegaly - CTD (SLE ... Associated - SLE ... • Bacterial endocarditis ... Differential #Diagnosis #hematology ... #rheumatology #
Differentiating NBTE from Infective Endocarditis
No pathognomonic signs/symptoms or echo features that are specific to NBTE, and
conditions: Autoimmune (SLE ... serology: Serial negative ... Frequent false-negative ... cultures/serology: + (Negative ... in up to 30% of cases
Causes of Thrombocytopenia - Differential Diagnosis Framework
Decreased Production:
 - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
Causes of Thrombocytopenia ... - Autoimmune: SLE ... valve replacement, endocarditis ... Diagnosis #Framework #hematology
Capnocytophaga
Pathogen: Capnocytophaga
 • 9 species, C. canimorsus responsible for the majority of infections
 • Gram-negative rod,
infections • Gram-negative ... ), Malignancy, SLE ... 13%), Pneumonia, Endocarditis ... microbiology #zoonotic #infectiousdiseases ... #diagnosis #management
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Discontinuation of causal ... pANCA anti-MPO - Negative ... Usual therapeutic management ... comparison #table #rheumatology ... #diagnosis #management