21 results
Oncologic Emergencies - Differential Diagnosis Framework

HEMATOLOGIC ONCOLOGIC EMERGENCIES:
Hyperviscosity Syndrome:
 • Spontaneous bleeding
 • Shortness of breath
Diagnosis Framework HEMATOLOGIC ... Hyperviscosity Syndrome ... Superior Vena Cava Syndrome ... : Tumor Lysis Syndrome ... Constipation • Nausea
Causes of Culture Negative Abscess - Differential Diagnosis Framework
Consider prior antibiotics as a cause of a
Causes of Culture ... antibiotics as a cause ... SAPHO, Sweet's Syndrome ... Auto-Inflammatory: SAPHO syndrome ... Differential #Diagnosis #InfectiousDiseases
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
Causes of false- ... negative SPEP: ... plasmacytoma, POEMs syndrome ... MGUS #diagnosis #hematology ... #oncology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... old, ~10,000 new cases ... Myelodysplastic #Syndrome ... Management #treatment #hematology ... #oncology
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
three primary pathophysiologic ... causes differentiated ... Pauci-immune mediated (Negative ... diagnosis #algorithm #rheumatology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
vs Tumor Lysis Syndrome ... Leukostasis: • Pathophysiology ... high WBC count cause ... : • Pathophysiology ... diagnosis #management #hematology
Noncardiogenic Pulmonary Edema - Differential Diagnosis Framework

NCPE Pathophysiology:
Noncardiogenic pulmonary edema occurs because of excessive pulmonary capillary
Framework NCPE Pathophysiology ... Causes include: ... • Normal or negative ... pg/ml EKG: • Negative ... respiratory distress syndrome
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Sweet Syndrome ... Causes: - Idiopathic ... , breast CA - Hematologic ... #diagnosis #dermatology ... #oncology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... ATRA treatment Pathophysiology ... Differentiation #Syndrome ... diagnosis #management #hematology ... #oncology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Constitutional Syndromes ... and petechiae Causes ... Constitutional Syndromes ... Aplastic #Anemia #oncology ... #hematology #diagnosis