39 results
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Pulmonary Renal ... Syndrome Definition ... Renal Syndromes ... polyangiitis) - ANCA-negative ... Complex: Systemic lupus
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... block • Sjogren syndrome ... Treatment: • ... #Systemic #Lupus ... #rheumatology #management
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... Diagnosis and Management ... pANCA anti-MPO - Negative ... life-threatening • Treatment ... Evolution: Chronic disease
Algorithm for Treatment of Chronic Thromboembolic Disease (CTEPH)
Initial Imaging for Screening - V/Q scan - 90-100%
Algorithm for Treatment ... Thromboembolic Disease ... karanpdesai #cteph #management ... #algorithm #cardiology ... #pulmonary #treatment
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
Post-strep GN, Lupus ... With associated pulmonary ... involvement: Anti-GBM Disease ... Pauci-immune mediated (Negative ... differential #diagnosis #algorithm
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Cerebrovascular Disease ... Puncture, EEG Treatment ... cerebritis #diagnosis #management ... #treatment
Management of interstitial lung disease (ILD)-associated with systemic sclerosis (SSc)

Therapeutic indication: absolute decline in FVC >10%
Management of interstitial ... lung disease (ILD ... systemicsclerosis #SSc #pulmonary ... #indications #management ... #treatment #algorithm
Tularemia - Diagnosis and Management Summary
Francisella tularensis - Aerobic fastidious gram-negative Coccobacillus - Zoonotic Infection
 •
Diagnosis and Management ... fastidious gram-negative ... Culture & GS, PCR Treatment ... : • Severe Disease ... #treatment #infectiousdiseases
Adjuvant therapies in critical care: steroids to treat infectious diseases
 - Severe Community Acquired Pneumonia
treat infectious diseases ... respiratory distress syndrome ... Corticosteroids #Adjuvant #InfectiousDiseases ... #Pharmacology #Management ... #Treatment #Indications
Algorithm for the Treatment of Membranous Lupus Nephritis
Sub-nephrotic-range proteinuria (<3.5g/d, normal serum albumin) and Preserved kidney
Algorithm for the ... Treatment of Membranous ... Lupus Nephritis ... for worsening disease ... #Treatment #management