49 results
Infective endocarditis - etiology and sources of infection. 
 • Native and prosthetic 
valve endocarditis
 •
Infective endocarditis ... • Native and ... prosthetic valve endocarditis ... #Sources #Causes ... #Differential #Microbiology
Causes of blood culture negative infective endocarditis

Bartonella spp, Brucella spp, Coxiella burnetii, Chlamydia spp, Tropheryma whipplei,
culture negative ... infective endocarditis ... #culture #negative ... #Endocarditis # ... InfectiousDiseases #Microbiology
Endocarditis Algorithm - Infective vs Noninfective Causes
Noninfective:
 • Malignancy
 • Autoimmune disease
 • Systemic infection
Native Valve
Endocarditis Algorithm ... vs Noninfective Causes ... HACEK • Culture-negative ... amzn.to/2LmUODZ #Endocarditis ... #Noninfective #Causes
HACEK is the acronym commonly used to describe and help doctors to remember a group of
fastidious Gram-negative ... which can also cause ... infective endocarditis ... is caused by HACEK ... is caused by Alpha-haemolytic
Streptocccus Pneumoniae
Microbiology: Gram Positive, Alpha-hemolytic, Catalase Negative
Epidemiology - 10% adult carriers:
 • Most common cause of:
Streptocccus Pneumoniae Microbiology ... Alpha-hemolytic, Catalase Negative ... • Most common cause ... media • Important cause ... peritonitis, and endocarditis
Epidemiological Clues That May be Helpful in Defining the Etiological Diagnosis of Culture-Negative Endocarditis

#Endocarditis #Bacteria #Differential
Epidemiological Clues ... Diagnosis of Culture-Negative ... Endocarditis ... #Endocarditis #Bacteria ... Microorganisms #Clues
My Patient with Infective Endocarditis (IE) Has Negative Blood Cultures
 - Did they receive antibiotics prior
with Infective Endocarditis ... (IE) Has Negative ... therapy - Number one cause ... of culture negative ... #Infective #Endocarditis
Differentiating NBTE from Infective Endocarditis
No pathognomonic signs/symptoms or echo features that are specific to NBTE, and
serology: Serial negative ... Frequent false-negative ... cultures/serology: + (Negative ... in up to 30% of cases ... #comparison #infective
Considerations for Crystalloids - 0.9% NS vs LR vs Plasma-Lyte
 - Causes hyperkalemia?
 - Safe to
Plasma-Lyte - Causes ... - Causes lactic ... - Can cause a NAGMA ... removed- trials were negative ... #indications #comparison
Endocarditis Summary

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV substance use
• IV catheter
• Recent
Hypercoagulable (APLAS) Microbiology ... positive in 90% of IE cases ... • Coagulase-negative ... Septic Emboli Cause ... Treat underlying cause