35 results
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... Inflammatory Conditions: Rheumatologic ... Vasculitides, IBD, Celiac disease ... Kawasaki, Nephrotic syndrome ... #Algorithm #hematology
Hyponatremia - Differential Diagnosis Algorithm
Hypovolemic - Give volume
Hypervolemic (Edematous) - Look for and treat underlying cause
Hyponatremia - Differential ... Diagnosis Algorithm ... cirrhosis, nephrotic syndrome ... #Algorithm #diagnosis ... #nephrology #sodium
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY

RED FLAGS - In all cases there are specific
markers which
suspicion of severe disease ... splenomegaly, abnormal neurology ... Rheumatology ... #Limping #NWB #Algorithm ... Peds #Pediatrics #Diagnosis
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation Syndrome ... highly inflammatory disease ... 10,000 ng/mL • Hyponatremia ... #Diagnosis #Management ... #Hematology #Rheumatology
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
and Differential Diagnosis ... Algorithm Consumption ... HLH syndrome 5. ... Metastatic Disease ... #Algorithm #Hematology
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
involvement: Anti-GBM Disease ... Pauci-immune mediated (Negative ... #differential #diagnosis ... #algorithm #rheumatology
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
ULN R - Renal disease ... Causes of false- negative ... plasmacytoma, POEMs syndrome ... Gammopathies #MGUS #diagnosis ... #hematology #oncology
Causes of Polycythemia (Erythrocytosis) - Differential Diagnosis Algorithm
Relative - Normal RBC Mass / Decreased Plasma Volume
- Differential Diagnosis ... Algorithm Relative ... #Differential #Diagnosis ... #Algorithm #Causes ... #Hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
and Differential Diagnosis ... Algorithm Consumption ... HLH syndrome 5 ... Metastatic Disease ... #Algorithm #Hematology
Iron Deficiency Anemia - Differential Diagnosis Algorithm

Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR

 • Blood loss:
- Differential Diagnosis ... Algorithm Labs ... Gastrectomy, WHDA syndrome ... Structural: Celiac disease ... #hematology