43 results
Autoimmune Hemolytic Anemia (AIHA) Pathophysiology - Warm vs Cold AIHA
Warm AIHA:
 - 70%; IgG mediated
 -
Anemia (AIHA) Pathophysiology ... C3 positive or negative ... mediated - DAT: IgG negative ... Hemolytic #Anemia #Pathophysiology ... #diagnosis #hematology
Coagulation Cascade and Anticoagulant Sites of Action

- Amy Chung, MD, MSc https://twitter.com/AmyChung

#AntiCoagulation #Cascade #Anticoagulants #Medications #Pharmacology
Amy Chung, MD, MSc ... #Pharmacology #Pathophysiology ... Mechanisms #DOAC #Hematology
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
three primary pathophysiologic ... Pauci-immune mediated (Negative ... diagnosis #algorithm #rheumatology
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm

Suspected TMA: Unexplained thrombocytopenia + MAHA
Diagnosis and Management ... normal • DAT negative ... Differential #Diagnosis #Management ... #Algorithm #hematology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Diagnosis and Management ... pANCA anti-MPO - Negative ... Usual therapeutic management ... Erythematosus #Diagnosis #Management ... #Summary #rheumatology
Approach to Gout
Diagnosis: r/o septic arthritis! Needle-shaped, negative birefringent crystals
Treatment:
 • Weight loss, diet, d/c culprit
Needle-shaped, negative ... gout #diagnosis #management ... treatment #ULT #rheumatology
Meralgia paresthetica: Pathogenesis and Clinical Findings
Compression/injury of Lateral Femoral Cutaneous Nerve (LFCN) -> Meralgia paresthetica
 •
Stabbing) - Negative ... MeralgiaParesthetica #MSK ... #pathophysiology
Difficult Airway Algorithm

1. Assess the likelihood and clinical impact of basic management problems: 
 • Difficulty
impact of basic management ... • Difficult mask ... difficult airway management ... Consider the relative ... #CriticalCare #Management
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Disease, PRES Pathophysiology ... CNS #neurology #rheumatology ... cerebritis #diagnosis #management
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
likelihood of negative ... indicator of infection relative ... neutrophil #WBC #CBC #hematology ... #pathophysiology