11 results
Consensus Indications for Irradiated RBC Transfusions:

Cellular blood components are irradiated for the prevention of TA-GVHD. Transfused
Transfusions: Cellular blood ... disorders (DiGeorge Syndrome ... HLA-selected products (e.g ... #Indications #Hematology ... #BloodBank #Management
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... : • Pathophysiology ... unless worrisome EKG ... TLS #diagnosis #management ... #hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
underlying disease (eg ... • Infection (eg ... Histopathologic criteria ... #Diagnosis #Management ... #Hematology #Rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Disease, PRES Pathophysiology ... thrombosis and/or blood-brain ... Lumbar Puncture, EEG ... cerebritis #diagnosis #management
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... ATRA treatment Pathophysiology ... Prednisone 5mg/kg ... APML #diagnosis #management ... #hematology #oncology
Hepatopulmonary Syndrome - Diagnosis and Management Summary
A defect in arterial oxygenation due to a gas exchange
Hepatopulmonary Syndrome ... passage • Arterial blood ... HPS Diagnostic Criteria ... hepatopulmonary #syndrome ... #treatment #hepatology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
in recipient (e.g ... antigens (often false negative ... (rare), false negatives ... Transfusions #diagnosis #management ... #hematology #reactions
Endocarditis Summary

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV substance use
• IV catheter
• Recent
• Coagulase-negative ... -> TEE • Duke Criteria ... ↑ ESR, CRP • EKG ... Endocarditis #diagnosis #management ... #cardiology
Endocarditis - Overview and Differential Diagnosis Framework

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV
Microbiology: Blood ... Cholesterol emboli syndrome ... → TEE • Duke Criteria ... ↑ ESR, CRP • EKG ... Differential #Diagnosis #cardiology
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... Pathophysiology ... Diagnostic Criteria ... of 8 HLH-2004 criteria ... #Hematology #HemeOnc