94 results
differential causes hematology management anemia pulmonary treatment autoimmune chronic classification hemolysis hepatology workup aiha celiac constipation criticalcare deficiency hypoxia injury
Autoimmune Hemolytic Anemia (AIHA) - Differential Diagnosis Table Warm AIHA (48-70%) Cold AHA (16-32%) • Donath-Landsteiner HA (paroxysmal
Autoimmune Hemolytic ... - Differential Diagnosis ... Agglutinin Disease ... AIHA (7-8%) DAT-negative ... #Autoimmune #Hemolytic
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... (e.g. primary cold ... agglutin disease ... e.g. sickle cell disease ... #differential #diagnosis
Autoimmune Hemolytic Anemia (AIHA) Pathophysiology - Warm vs Cold AIHA Warm AIHA: - 70%; IgG mediated -
Autoimmune Hemolytic ... C3 positive or negative ... mediated - DAT: IgG negative ... AIHA #Autoimmune #Hemolytic ... Pathophysiology #diagnosis
Expected DAT Results in Autoimmune Hemolysis DAT Negative Hemolysis • DAT Poly ( - ), IgG (
in Autoimmune Hemolysis ... DAT Negative Hemolysis ... , C3d ( +/- ) Cold ... agglutinin disease ... #hematology #diagnosis
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
- Differential Diagnosis ... Algorithm Extravascular ... Warm AIHA • Cold ... #Differential #Diagnosis ... #Algorithm #Causes
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
- Differential Diagnosis ... Algorithm • Sickle ... Agglutination - Cold ... #Differential #Diagnosis ... #Algorithm #workup
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Disease 3 Types ... Diagnosis: • hemolytic ... for anti-C3d and negative ... • Compensated hemolysis ... #hemolytic #anemia
Hemolytic Anemia - Differential Diagnosis Algorithm Hereditary: • Peripheral blood smear + DAT + further History •
- Differential Diagnosis ... Algorithm Hereditary ... malignancy, autoimmune disease ... #Differential #Diagnosis ... #Algorithm #causes
Pulmonary Function Testing (PFT) Interpretation Algorithm Restrictive Lung Disease: • Chest wall or neuromuscular disorders • Interstitial
Interpretation Algorithm ... Emphysematous COPD ... Interpretation #Algorithm ... #diagnosis #asthma ... #COPD
Pulmonary Function Tests (PFTs) - Interpretation Algorithm • Normal • Pulmonary Hypertension, Anemia, Carboxyhemoglobinemia • Chest
Interpretation Algorithm ... Interstitial Lung Disease ... Non-Emphysematous COPD ... Emphysematous COPD ... #diagnosis
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