8 results
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Liver Injury (DILI ... ) DILI Types: ... symptoms of liver disease ... Diagnosis #Management #gastroenterology ... #algorithm #gastroenterology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Liver Injury (DILI ... Stepwise Diagnosis Algorithm ... Alcohol-related liver disease ... biopsy if: • Negative ... Injury #Diagnosis #Algorithm
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
of SLE versus DIL ... pANCA anti-MPO - Negative ... Evolution: Chronic disease ... Management #Summary #rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Induced Lupus (DIL ... rash is rare in DIL ... pANCA anti-MPO - Negative ... Evolution: Chronic disease ... comparison #table #rheumatology
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
involvement: Anti-GBM Disease ... Pauci-immune mediated (Negative ... differential #diagnosis #algorithm ... #rheumatology
Causes of Polycythemia (Erythrocytosis) - Differential Diagnosis Algorithm
Relative - Normal RBC Mass / Decreased Plasma Volume
Differential Diagnosis Algorithm ... Relative - Normal ... Cyanotic Heart Disease ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
Onset Still's Disease ... dysfunction, and negative ... anti-lL6R, anti-ILI ... onset #Stills #disease ... AOSD #diagnosis #rheumatology
Celiac Disease - Diagnosis Algorithm
IgA TTG has high sensitivity and specificity of ~ 98% and is
Celiac Disease - ... Diagnosis Algorithm ... -A negative test ... - Gastroenterology ... #gastroenterology