16 results
Daptomycin  - Antibiotics Class Overview

Mechanism: Lipopeptide antibiotic – forms transmembrane channels and depolarizes cells.
Class Overview ... No gram negative ... skin/soft tissue infections ... MRSA bacteremia/endocarditis ... cidal nature) #Pharmacology
Aminoglycosides  - Antibiotics Class Overview

Gentamicin, Tobramycin, Amikacin, Streptomycin -30S inhibitor (all IV)
Spectrum: Extremely efficacious vs.
Aminoglycosides - Antibiotics ... Class Overview ... effect (mainly in endocarditis ... #Pharmacology #Antibiotics ... #Review #Overview
Carbapenems - Antibiotics Class Overview

Imipenem/Cilastin, Meropenem, Ertapenem, Doripenem 

Spectrum: Broadest spectrum antibiotics, cover Gram positive, Gram
Class Overview ... positive, Gram negative ... resistant gram negatives ... #Pharmacology ... #Overview #Carbapenems
Infective endocarditis - etiology and sources of infection. 
 • Native and prosthetic 
valve endocarditis
 •
and sources of infection ... • Native and ... • Soft tissue infections ... for TPN) and antibiotic ... Bacteria #Etiology #Differential
Tigecycline (IV) - Antibiotics Class Overview

Mechanism: Glycylcycline class - structurally related to Tetracyclines (bacteriostatic).  Only
Tigecycline (IV) - Antibiotics ... Class Overview ... and VRE), Gram negatives ... #Pharmacology #Antibiotics ... #Review #Overview
Vancomycin and Dalbavancin (lipoglycopeptide antibiotics) - Antibiotics Class Overview

Mechanism: Glycopeptide -  inhibits cell wall synthesis
) - Antibiotics ... Class Overview ... No gram negative ... #Pharmacology #Antibiotics ... #Review #Overview
Flutycosine - Antibiotics Class Overview
 - 
Mechanism: 5-FC interferes with DNA and protein synthesis.  Only
Flutycosine - Antibiotics ... Class Overview ... (endocarditis, ... #Pharmacology #Antibiotics ... #Review #Overview
Causes of Fatigue - Differential Diagnosis Algorithm
Endocrine
 • Hypo/Hyperthyroidism
 • Diabetes
 • Pituitary Insufficiency
 • Adrenal
Causes of Fatigue - Differential ... Hyperthyroidism • Diabetes ... • Malignancy Infectious ... • Endocarditis ... Myasthenia Gravis Pharmacologic
Monobactam - Aztreonam - Antibiotics Class Overview

Spectrum: only has activity vs. aerobic gram negatives, no gram
Class Overview ... . aerobic gram negatives ... due to gram-negative ... #Pharmacology #Antibiotics ... #Review #Overview
Endocarditis Summary

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV substance use
• IV catheter
• Recent
Infectious: • Pre-existing ... devices (CIED) Non-Infectious ... • Coagulase-negative ... Marantic (NTBE) Differential ... • IV Antibiotics