26 results
hematology algorithm symptoms treatment cardiology hemolytic sle autoimmune classification comparison criticalcare erythematosus summary systemic vasculitis workup abscess aiha antibody aortoenteric
Autoimmune Hemolytic Anemia (AIHA) - Differential Diagnosis Table Warm AIHA (48-70%) Cold AHA (16-32%) • Donath-Landsteiner HA (paroxysmal
(AIHA) - Differential ... Diagnosis Table ... AIHA (7-8%) DAT-negative ... #Diagnosis #Table ... #hematology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
- Hemolytic anemia ... (aPL) 30-45% Differential ... Diagnosis and Lupus ... autoantibodies #signs ... #rheumatology
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
1) DIAGNOSE AIHA ... • Blood smear: Differential ... 2) LOOK FOR a cause ... #diagnosis #management ... #treatment #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... Positive in 60-80% of cases ... pANCA anti-MPO - Negative ... Erythematosus #Diagnosis ... #rheumatology
Causes of Isolated Neutropenia - Differential Diagnosis Algorithm Congenital Medications • Anticonvulsants • Antibiotics • Antithyroid • Antihypertensive
Causes of Isolated ... Diagnosis Algorithm ... Bacteria • Gram Negative ... Destruction • Systemic Lupus ... #Causes #Hematology
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
pathophysiologic causes ... Post-strep GN, Lupus ... Pauci-immune mediated (Negative ... #diagnosis #algorithm ... #rheumatology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... usually IgG) (e.g. lupus ... #differential # ... diagnosis #hematology ... #anemia
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
pANCA anti-MPO - Negative ... Usual therapeutic management ... sle #comparison #table ... #rheumatology # ... diagnosis #management
Features That Differentiate Acute Pericarditis from Myocardial Ischemia or Infarction and Pulmonary Embolism In contrast to the
associated with rheumatologic ... presentation of systemic lupus ... life-threatening causes ... Pericarditis #Symptoms #Signs ... #Diagnosis
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 Hemorrhagic Pericardial Effusions (Hemopericardium)- Differential Diagnosis Framework IATROGENIC DISEASE Secondary to invasive cardiac procedures NONIATROGENIC • Malignancy (e.g., metastatic spread:
Diagnosis Framework ... OTHER RARE CAUSES ... amyloidosis • Uremia ... induced • MCTD, Lupus ... may have false negative
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