72 results
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Differential Diaqnoses ... hepatitis • Pulmonary ... • Ocular: uveitis ... #management #treatment ... #rheumatology
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm

Suspected TMA: Unexplained thrombocytopenia + MAHA
- Differential Diagnosis ... and Management ... normal • DAT negative ... #Management #Algorithm ... #hematology
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Pulmonary Renal ... Differential Diagnosis ... polyangiitis) - ANCA-negative ... resolution chest CT ... #differential #diagnosis
Rheumatoid Arthritis - 2020 ACR-EULAR Classification
≥ 6 of 10 points = definite RA
Joint Involvement:
Arthritis - 2020 ACR-EULAR ... at least 1): Negative ... RF, negative anti ... Rheumatoid #Arthritis #diagnosis ... #rheumatology
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
With associated pulmonary ... Pauci-immune mediated (Negative ... #differential #diagnosis ... #algorithm #rheumatology
Etiologies of pulmonary infections according to CT-scan patterns. 
CMV cytomegalovirus, GM galactomannan, HSV herpes simplex virus,
Etiologies of pulmonary ... infections according to CT-scan ... Varicella–Zoster virus NODULAR ... #Patterns #Pulmonary ... #Differential #Diagnosis
Approach to Gout
Diagnosis: r/o septic arthritis! Needle-shaped, negative birefringent crystals
Treatment:
 • Weight loss, diet, d/c culprit
Approach to Gout Diagnosis ... Needle-shaped, negative ... NUIM_Chiefs #gout #diagnosis ... #management #treatment ... #ULT #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Erythematosus (SLE) - Diagnosis ... and Management ... pANCA anti-MPO - Negative ... Erythematosus #Diagnosis ... #rheumatology
High-Res Chest CT Patterns - Differential Diagnosis Framework
Reticular:
 • Septal Thickening: Lymphangitic Carcinoma, Interstitial Edema, Alveolar
High-Res Chest CT ... - Differential Diagnosis ... Low Attenuation Nodular ... HighRes #Chest #CT ... #pulmonary #radiology
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
concentration PET-CT ... Imaging (→ Diagnostic ... • Some false negative ... #management #phenotypes ... workup #treatment #rheumatology