18 results
Approach to Neonatal Jaundice

Causes of pathologic hyperbilirubinemia can be classified as due to (1) increased bilirubin
Approach to Neonatal ... Jaundice Causes ... Peds #Pediatrics #Neonatal ... #Jaundice #Algorithm ... #Differential #
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Function Tests - Differential ... Diagnosis Algorithm ... Congenital, Others, Cirrhosis ... Transaminitis #Algorithm ... #diagnosis #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Diagnosis Algorithm ... • Pregnancy - AFLP ... Infiltrative • Cirrhosis ... Others #LFTs #Hepatology ... #Causes
Primary Biliary Cirrhosis - Diagnosis Algorithm
Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort
Signs: Jaundice, Xanthelasmata, Hepatomegaly
Associated history:
Primary Biliary Cirrhosis ... - Diagnosis Algorithm ... discomfort Signs: Jaundice ... Elevated ALP 2. ... #hepatology
Jaundice - Differential Diagnosis Algorithm
Pre-Hepatic - Unconjugated Hyperbilirubinemia
Increased Production
 • Hemolysis
 • Ineffective Erythropoiesis
 • Hematoma
Decreased
Jaundice - Differential ... Diagnosis Algorithm ... #Differential # ... Diagnosis #Algorithm ... #Causes #Hepatology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... = nonspecific (nausea ... (DIC, ascites, jaundice ... infiltration) Differential ... Liver #Pregnancy #hepatology
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
) Elevation - Differential ... Diagnosis Algorithm ... Intestine - Other causes ... #Diagnosis #Algorithm ... #hepatology
Causes of Splenomegaly - Differential Diagnosis Algorithm
Infectious
 • Bacterial
 • Viral (EBV)
 • Parasitic
 • Fungal
Congestive
- Differential ... Diagnosis Algorithm ... Congestive • Cirrhosis ... #Diagnosis #Algorithm ... #Causes #Hematology
Hepatomegaly - Differential Diagnosis Algorithm
Malignant
 • Primary Carcinoma
 • Metastases
 • Lymphoma
 • Leukemia
 • Polycythemia
Hepatomegaly - Differential ... Diagnosis Algorithm ... Primary Biliary Cirrhosis ... #Diagnosis #Algorithm ... #Causes #Hepatology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
intralobular bile ducts causes ... hyperpigmentation • Jaundice ... obstruction • ALP ... bile ducts Differential ... diagnosis #workup #hepatology