17 results
NSAIDS and their effects on the Kidney - Pathophysiology

Arachidonic Acid metabolites into alternative pathways that modify
on the Kidney - Pathophysiology ... modify immune function ... distal component of Nephron ... absorption in distal nephron ... nephrology #Effects #pathophysiology
Major Segments of the Nephron and their Functions 
 - Glomerulus - Formation of glomerular filtrate
Segments of the Nephron ... and their Functions ... organic acids and bases ... vasopressin control #Nephron ... #Pathophysiology
Pathophysiology of hypotonic hyponatremia

by Helbert Rondon, MD @NephroMD

#hypotonic #hyponatremia #nephrology #algorithm #Pathophysiology
Pathophysiology ... Helbert Rondon, MD @NephroMD ... hyponatremia #nephrology #algorithm ... #Pathophysiology
Hyperuricemia: Pathogenesis and Complications

 - Hypercalcemia (due to diseases like Sarcoidosis and Hyperparathyroidism) -> Accumulation of
arteriole in the nephron ... tubule in the nephron ... blood into the nephron ... Release of purine bases ... Hyperuricemia #Pathophysiology
Differential Diagnosis and Evaluation of Hyponatremia:
1) Identification of onset (acute vs. chronic)
2) Presence of symptoms (HA,
symptoms (HA, nausea ... Diagnosis #EM #IM #Nephro ... #Differential #Algorithm
Hyponatremia Diagnosis Algorithm
UOsm ≥ POsm - Vasopressin-Dependent
 • UNa < 20 mEq/L - Appropriate (↓ EABV)
Hyponatremia Diagnosis Algorithm ... Helbert Rondon, MD @NephroMD ... #differential #algorithm ... #causes #nephrology
Causes of Peripheral Weakness - With and Without Sensory Changes - Differential Diagnosis Algorithm
With Sensory Changes:
Causes of Peripheral ... Differential Diagnosis Algorithm ... Weakness • Motor Neuron ... Neuromuscular Junction ... #Causes
Hypochloremia - Differential Diagnosis Algorithm

Cause - Decreased Intake:
 • Low salt in diet
 • Exclusive D5W
Differential Diagnosis Algorithm ... transport, renal function ... Gastrointestinal function ... Differential #Diagnosis #Algorithm ... #Pathophysiology
Causes of Peripheral Weakness without Sensory Changes - Differential Diagnosis Algorithm
No Objective Weakness
 • Cardio-pulmonary disease
Causes of Peripheral ... Differential Diagnosis Algorithm ... Disease Motor Neuron ... Neuromuscular Junction ... #Causes
SGLT2 Inhibitors 
SGLT2 inhibitors are the newest class of anti-diabetic medications, with the first one (Canagliflozin)
reabsorption in the nephron ... kidney), which causes ... have good kidney function