16 results
NSAIDS and their effects on the Kidney - Pathophysiology

Arachidonic Acid metabolites into alternative pathways that modify
on the Kidney - Pathophysiology ... modify immune function ... distal component of Nephron ... absorption in distal nephron ... Idiosyncratic immune reaction
Hypochloremia - Differential Diagnosis Algorithm

Cause - Decreased Intake:
 • Low salt in diet
 • Exclusive D5W
Differential Diagnosis Algorithm ... Ileostomy - NGT suction ... - Diarrhea • RENAL ... gas transport, renal ... #Pathophysiology
NSAID vs ACEI/ARB effects on the Kidneys

Remember that NSAIDs and ACEI/ARB therapy have opposing effects on
NSAIDs cause vasoconstriction ... normal kidney function ... use shouldn't cause ... Effects #Nephrology #Renal ... #Pathophysiology
Causes of High-anion Gap and Non-anion Gap Metabolic Acidosis
Causes of High-anion Gap Acidosis:
 • Lactic acidosis
Causes of High-anion ... oxoproline) • Renal ... Renal acidosis ... Generalized distal nephron ... ACE-Is and ARBs
Major Segments of the Nephron and their Functions 
 - Glomerulus - Formation of glomerular filtrate
Segments of the Nephron ... and their Functions ... organic acids and bases ... #Segments #Function ... #Pathophysiology
Major Physiological Effects of Angiotensin II

Altered Peripheral Resistance
I. Direct vasoconstriction
II. Enhancement of peripheral noradrenergic
neurotransmission:
  A.
Function l. ... excretion in distal nephron ... Increased renal ... AngiotensinII #Pathophysiology ... #Action
Hyperuricemia: Pathogenesis and Complications

 - Hypercalcemia (due to diseases like Sarcoidosis and Hyperparathyroidism) -> Accumulation of
of calcium in renal ... tubules - ACE-inhibitors ... arteriole in the nephron ... Release of purine bases ... Hyperuricemia #Pathophysiology
Causes of Metabolic Alkalosis - Differential Diagnosis Algorithm
GI Losses - Gastric
 • Vomiting
 • NG suction
GI
Causes of Metabolic ... Vomiting • NG suction ... Chloridorrhea Renal ... • Penicillins Renal ... #Causes
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
Differential Diagnosis Algorithm ... Vomiting, NGT suction ... hyperaldosteronism • High PRA: Renal ... Differential #Diagnosis #Algorithm ... #Nephrology #Causes
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings
 • Note: in DKA, body K+ is lost
out of cells may cause ... patient has good renal ... function/urine ... 3) Follow the anion ... DiabeticKetoacidosis #DKA #pathophysiology