11 results
NSAIDS and their effects on the Kidney - Pathophysiology

Arachidonic Acid metabolites into alternative pathways that modify
NSAIDS and their effects ... on the Kidney - Pathophysiology ... modify immune function ... KidneyDisease #nephrology ... #Effects #pathophysiology
Major Segments of the Nephron and their Functions 
 - Glomerulus - Formation of glomerular filtrate
Segments of the Nephron ... and their Functions ... acid and most diuretics ... #Segments #Function ... #Pathophysiology
NSAID vs ACEI/ARB effects on the Kidneys

Remember that NSAIDs and ACEI/ARB therapy have opposing effects on
NSAID vs ACEI/ARB effects ... have opposing effects ... normal kidney function ... #Nephrology #Renal ... #Pathophysiology
Hypochloremia - Differential Diagnosis Algorithm

Cause - Decreased Intake:
 • Low salt in diet
 • Exclusive D5W
RENAL LOSS: - Diuresis ... transport, renal function ... Gastrointestinal function ... #Pathophysiology ... #Nephrology #Chloride
SGLT2 Inhibitors 
SGLT2 inhibitors are the newest class of anti-diabetic medications, with the first one (Canagliflozin)
reabsorption in the nephron ... drugs include side effects ... are similar to diuretics ... Side effects include ... have good kidney function
Major Physiological Effects of Angiotensin II

Altered Peripheral Resistance
I. Direct vasoconstriction
II. Enhancement of peripheral noradrenergic
neurotransmission:
  A.
Physiological Effects ... Altered Renal Function ... Direct effect to ... excretion in distal nephron ... AngiotensinII #Pathophysiology
Hepatorenal Syndrome (HRS)

Definition:
• Functional, potentially reversible kidney impairment.
• Occurs in advanced liver disease: cirrhosis, severe alcoholic
Definition: • Functional ... Pathophysiology: ... • Tubular function ... volume expansion + diuretic ... Syndrome #Hepatology #Nephrology
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
loss of motor function ... Preserved motor function ... loss of motor function ... and lower motor neuron ... Syndromes #diagnosis #pathophysiology
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
Urinary Chloride Algorithm ... loop or thiazide diuretics ... pressure: Active diuretic ... mineralocorticoid-like effect ... #nephrology #differential
Types of Facial Paralysis - Peripheral vs Central Lesions

Facial weakness or paralysis may result either from
the upper motor neuron ... their different effects ... face continues to function ... #Bells #Palsy #Neurology