16 results
NSAIDS and their effects on the Kidney - Pathophysiology

Arachidonic Acid metabolites into alternative pathways that modify
NSAIDS and their effects ... on the Kidney - Pathophysiology ... modify immune function ... KidneyDisease #nephrology ... #Effects #pathophysiology
Diuretics - Pharmacology

Thiazides diuretics:
 • Inhibit Na+ Cl- cotransporter in distal tubule
 • Chlorothiazide, Chlorthalidone, Indapamide,
Diuretics - Pharmacology ... loss through the nephron ... as no effect on ... #Pharmacology #nephrology ... loop #thiazide #classes
Major Segments of the Nephron and their Functions 
 - Glomerulus - Formation of glomerular filtrate
Segments of the Nephron ... and their Functions ... organic acids and bases ... acid and most diuretics ... #Pathophysiology
NSAID vs ACEI/ARB effects on the Kidneys

Remember that NSAIDs and ACEI/ARB therapy have opposing effects on
NSAIDs cause vasoconstriction ... normal kidney function ... use shouldn't cause ... #Nephrology #Renal ... #Pathophysiology
Hypochloremia - Differential Diagnosis Algorithm

Cause - Decreased Intake:
 • Low salt in diet
 • Exclusive D5W
Differential Diagnosis Algorithm ... RENAL LOSS: - Diuresis ... Differential #Diagnosis #Algorithm ... #Pathophysiology ... #Nephrology #Chloride
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
Differential Diagnosis Algorithm ... Vomiting, NGT suction ... Low Cl intake, Diuretics ... High Urine Cl-: Diuretics ... #Nephrology #Causes
SGLT2 Inhibitors 
SGLT2 inhibitors are the newest class of anti-diabetic medications, with the first one (Canagliflozin)
reabsorption in the nephron ... kidney), which causes ... are similar to diuretics ... Side effects include ... have good kidney function
Causes of Peripheral Weakness - With and Without Sensory Changes - Differential Diagnosis Algorithm
With Sensory Changes:
Causes of Peripheral ... Weakness • Motor Neuron ... Neuromuscular Junction ... Weakness #Sensory #Neurology ... #Causes
Hepatorenal Syndrome (HRS)

Definition:
• Functional, potentially reversible kidney impairment.
• Occurs in advanced liver disease: cirrhosis, severe alcoholic
Definition: • Functional ... • Caused by splanchnic ... Pathophysiology: ... • Tubular function ... Syndrome #Hepatology #Nephrology
Metabolic Alkalosis - Differential Diagnosis Algorithm - Urinary Chloride
 • Cl- responsive metabolic alkalosis
Differential Diagnosis Algorithm ... loop or thiazide diuretics ... Vomiting/nasogastric suction ... mineralocorticoid-like effect ... #causes #urinary