10 results
Nephron Remodeling as a Mechanism of Diuretic Resistance. When high doses of loop diuretics are used
a Mechanism of Diuretic ... Resistance. ... doses of loop diuretics ... #Pathophysiology ... #Nephro #IM #LoopDiuretic
Mechanisms of Loop Diuretic Action and Resistance. Panel A, loop diuretics circulate bound to protein. As
Mechanisms of Loop Diuretic ... Action and Resistance ... resistance. ... #Pathophysiology ... #Nephro #IM #LoopDiuretic
Mechanisms of nephron damage in cardiorenal syndrome
 • Increased renal interstitial pressure
 • Hypoperfusion
 • Reduced
Mechanisms of nephron ... activities • Diuretic ... resistance • ... syndrome #Mechanisms #pathophysiology
Major Segments of the Nephron and their Functions 
 - Glomerulus - Formation of glomerular filtrate
Segments of the Nephron ... and their Functions ... acid and most diuretics ... #Segments #Function ... #Pathophysiology
Causes of Metabolic Alkalosis - Differential Diagnosis Algorithm
Urine chloride < 20 mmol/l - Chloride responsive (Chloride
Differential Diagnosis Algorithm ... Vomiting • NG suction ... fibrosis • Remote diuretic ... mmol/l - Chloride resistant ... : • Current diuretic
Metabolic Alkalosis - Differential Diagnosis Algorithm - Urinary Chloride
 • Cl- responsive metabolic alkalosis
Differential Diagnosis Algorithm ... loop or thiazide diuretics ... Vomiting/nasogastric suction ... fibrosis) • Cl- resistant ... pressure: Active diuretic
Hepatorenal Syndrome (HRS)

Definition:
• Functional, potentially reversible kidney impairment.
• Occurs in advanced liver disease: cirrhosis, severe alcoholic
Definition: • Functional ... Pathophysiology: ... • Tubular function ... volume expansion + diuretic ... Associated with diuretic-resistant
Hypochloremia - Differential Diagnosis Algorithm

Cause - Decreased Intake:
 • Low salt in diet
 • Exclusive D5W
Differential Diagnosis Algorithm ... RENAL LOSS: - Diuresis ... transport, renal function ... Gastrointestinal function ... #Pathophysiology
Major Physiological Effects of Angiotensin II

Altered Peripheral Resistance
I. Direct vasoconstriction
II. Enhancement of peripheral noradrenergic
neurotransmission:
  A.
Altered Peripheral Resistance ... Altered Renal Function ... excretion in distal nephron ... AngiotensinII #Pathophysiology
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
Urinary Chloride Algorithm ... loop or thiazide diuretics ... fibrosis Cl- resistant ... pressure: Active diuretic ... responsive and resistant