9 results
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
pathophysiologic causes ... Complement: IgA nephropathy ... With associated pulmonary ... differential #diagnosis #algorithm ... #rheumatology
Causes of Peripheral Weakness without Sensory Changes - Differential Diagnosis Algorithm
No Objective Weakness
 • Cardio-pulmonary disease
Causes of Peripheral ... Differential Diagnosis Algorithm ... Weakness • Cardio-pulmonary ... Differential #Diagnosis #Algorithm ... #Causes
Erythrocytosis - Polycythemia Differential Diagnosis Algorithm

Elevated Hemoglobin:
 • Males: Hb > 16.5 g/dL/HCT ≥ 49%
 •
Differential Diagnosis Algorithm ... Polycythemia - Acquired Causes ... Hypoxia-driven: Cardiac/pulmonary ... Differential #Diagnosis #Algorithm ... #hematology
Causes of Polycythemia (Erythrocytosis) - Differential Diagnosis Algorithm
Relative - Normal RBC Mass / Decreased Plasma Volume
Causes of Polycythemia ... Differential Diagnosis Algorithm ... Cyanosis without Pulmonary ... Apnea • Chronic Pulmonary ... #Causes #Hematology
Syncope - Differential Diagnosis Algorithm
Neurocardiogenic:
 • Vasovagal
 • Orthostatic Hypotension
 • Autonomic Neuropathy
 • Situational (micturition,
Differential Diagnosis Algorithm ... • Autonomic Neuropathy ... Respiratory: • Pulmonary ... Differential #Diagnosis #Algorithm ... #causes
Anterior ischemic optic neuropathy (AION) - Recognition of giant cell arteritis (GCA)

1) Is visual loss caused
ischemic optic neuropathy ... Is visual loss caused ... the optic nerve caused ... GiantCellArteritis #GCA #Rheumatology ... Ophthalmology #Diagnosis #Algorithm
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
progressing GN • New pulmonary ... glomerulonephritis and/or pulmonary ... tract, and often causes ... arthritis, obstructive pulmonary ... differential #diagnosis #rheumatology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
progressing GN • New pulmonary ... MPO > PR3) • Pulmonary ... tract, and often causes ... Ig A nephropathy ... Differential #Diagnosis #Rheumatology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... Xerostomia • Dental caries ... Disease: • 10%-15% Pulmonary ... , INC risk PE, Pulmonary ... Sjogrens #Syndrome #Rheumatology