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diagnosis management differential blood hemolytic product syndrome activation aplastic classification comparison dress extravascular hemolysis intravascular macrophage mas monkeypox mpox neutropenia
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Treatment: • Consider ... Supportive care (transfusions ... antibiotics if neutropenic ... diagnosis #management #treatment ... #hematology
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
for Hemolytic Anemia ... prosthetic valve • Transfusion ... reactions ex. ... #Hemolytic #Anemia ... classification #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... reaction, Paroxysmal ... Extravascular #Causes ... differential #diagnosis #hematology ... #anemia
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
maculopapular rash ... Causes purpura & ... TRALI): Leading cause ... more likely to cause ... diagnosis #management #hematology
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
Reactions TRALI ... without other cause ... : 33% • Treatment ... : No • Treatment ... #Reactions #hematology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
maculopapular rash ... Causes purpura & ... TRALI): Leading cause ... more likely to cause ... diagnosis #management #hematology
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Definition: • Severe adverse drug reaction, characterized by
Drug Reaction with ... extensive skin rash ... Edema in 70% of cases ... disease: symptomatic treatment ... DRESS #Syndrome #dermatology
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
hypertension and/or drug treatment ... Idiosyncratic drug reactions ... Megaloblastic anemia-rare ... Idiosyncratic drug reactions-most ... #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Petechial or purpuric rash ... with leukopenia, anemia ... 10,000 ng/mL • Hyponatremia ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology
Monkeypox What? Monkeypox virus belongs to the family Poxviridae, subfamily Chordopoxvirinae, and genus orthopoxvirus Viral zoonotic disease that is
disease that is caused ... Characteristic Rash ... Polymerase chain reaction ... Respiratory distress Treatment ... Diagnosis #Management #Dermatology
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