30 results
Causes of Hypernatremia - Differential Diagnosis
Inadequate water intake:
 • Lack of access to water
Extrarenal hypotonic fluid
Causes of Hypernatremia ... - Differential ... insipidus • Nephrogenic ... Diagnosis #Causes #nephrology ... #sodium #high
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
Differential Diagnosis ... Workup Algorithm 1) ... renal mechanism 2) ... • Euvolemic: Diabetes ... #sodium
Hypernatremia Differential Diagnosis Algorithm - Diabetes Insipidus Workup

Step #1 - Consider the history
Step #2 - Assess
Hypernatremia Differential ... Workup Step #1 ... history Step #2 ... Uglucose Step #3 ... #Sodium #nephrology
Hypernatremia - Differential Diagnosis and Treatment
Hypernatremia is almost always due to unreplaced water loss (free water
Osmotic Diuresis ... post-obstructive 3) ... Diabetes Insipidus ... : neurogenic, nephrogenic ... #nephrology #sodium
Hypernatremia Diagnosis and Workup

Step 1 . Repeat the sodium concentration.
Step 2.  Check plasma osmolality.
NORMAL PLASMA
Workup Step 1 ... Repeat the sodium ... Step 2. ... administration Step 3. ... volume loss - diuretics
Hyponatremia Differential Diagnosis Algorithm - Utilizing Uric Acid 
ADH promotes Urea/uric acid excretion along with water
Hyponatremia Differential ... water retention 1) ... Serum Osmolarity 2) ... Urine Osmolarity 3) ... Urine Sodium 4)
Cerebral Salt Wasting vs SIADH - Pathophysiology 
1) Neurological event
2) Sodium loss from tubules
3) Naturiesis →
Pathophysiology 1) ... Neurological event 2) ... Sodium loss from ... tubules 3) Naturiesis ... #hyponatremia #
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
+K / serum Na >1 ... : SIADH, Renal Sodium ... #differential # ... diagnosis #table ... #sodium #nephrology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
irrigation • Management ... nephrotic syndrome • Hyponatremia ... and euvolemic hyponatremia ... #Nephrology #Pharmacology ... #Medications #Table
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
cell epithelial sodium ... of epithelial sodium ... diabetes insipidus ... #Diagnosis #Differential ... #Table