13 results
Hypernatremia Differential Diagnosis Algorithm - Diabetes Insipidus Workup

Step #1 - Consider the history
Step #2 - Assess
Hypernatremia Differential ... Uglucose Step #3 ... Eric Strong @DrEricStrong ... Management #Algorithm #Sodium ... #nephrology #insipidus
Causes of Hypernatremia - Differential Diagnosis
Inadequate water intake:
 • Lack of access to water
Extrarenal hypotonic fluid
Causes of Hypernatremia ... - Differential ... • Nephrogenic ... Diagnosis #Causes #nephrology ... #sodium #high
Etiologies of Hypernatremia - Differential Diagnosis
GI losses / Insensible losses
Sodium Overload
Transcellular Movement of Water
Central Diabetes Insipidus
Etiologies of Hypernatremia ... - Differential ... Insensible losses Sodium ... Eric Strong https ... Diagnosis #Table
Hypernatremia - Differential Diagnosis and Treatment
Hypernatremia is almost always due to unreplaced water loss (free water
, Dehydration: neurologic ... post-obstructive 3) ... Diabetes Insipidus ... : neurogenic, nephrogenic ... #sodium
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
Differential Diagnosis ... Euvolemic: Diabetes insipidus ... (central or nephrogenic ... #Differential # ... #sodium
Hyponatremia - Differential Diagnosis by Mechanism
Decr Blood Pressure (“Decr Effective Circulating Volume”) 
 - Volume depletion
Hyponatremia - Differential ... depletion - Heart ... #Differential # ... Diagnosis #Table ... #Causes #Sodium
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
cell epithelial sodium ... of epithelial sodium ... diabetes insipidus ... #Diagnosis #Differential ... #Table
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework

Heat Cramps:
 • Muscle pain or spasm -
Heat Stroke - Differential ... Dehydration - Loss of sodium ... conditions - Neurogenic ... illness → Hypernatremia ... , ARDS, DIC) 3.
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
nephrotic syndrome • Hyponatremia ... Tolvaptan) • Treatment ... and euvolemic hyponatremia ... Excretion #Diuresis #Nephrology ... #Medications #Table
Hyponatremia - Diagnosis and Treatment
Hyponatremia is usually caused by the inability to excrete water normally.
Then, ask 3 questions ... approach to the differential ... #Differential # ... #management #nephrology ... #sodium