36 results
Hypernatremia Differential Diagnosis Algorithm - Diabetes Insipidus Workup

Step #1 - Consider the history
Step #2 - Assess
Hypernatremia Differential ... history Step #2 ... Uglucose Step #3 ... #Management #Algorithm ... #Sodium #nephrology
Causes of Hypernatremia - Differential Diagnosis
Inadequate water intake:
 • Lack of access to water
Extrarenal hypotonic fluid
Causes of Hypernatremia ... - Differential ... • Nephrogenic ... Diagnosis #Causes #nephrology ... #sodium #high
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
Differential Diagnosis ... renal mechanism 2) ... Euvolemic: Diabetes insipidus ... Workup #Algorithm #nephrology ... #sodium
Hypernatremia - Differential Diagnosis and Treatment
Hypernatremia is almost always due to unreplaced water loss (free water
water unavailable 2) ... post-obstructive 3) ... Diabetes Insipidus ... : neurogenic, nephrogenic ... #nephrology #sodium
Hyponatremia Differential Diagnosis Algorithm - Utilizing Uric Acid 
ADH promotes Urea/uric acid excretion along with water
Hyponatremia Differential ... Serum Osmolarity 2) ... Urine Osmolarity 3) ... Urine Sodium 4) ... Diagnosis #Algorithm #nephrology
Causes of Hypernatremia - Differential Diagnosis Algorithm
Hypernatremia - Excess free water loss, Serum Sodium >145 mmol/L
High
Causes of Hypernatremia ... - Differential ... water loss, Serum Sodium ... kg • Diabetes Insipidus ... #Nephrology #Differential
Classification of Diabetes Insipidus

Central or neurogenic diabetes insipidus:
 - Congenital - Structural malformations affecting the hypothalamus
Central or neurogenic ... Surgery, Idiopathic Nephrogenic ... mutations in AQP-2 ... Classification #Types #Nephrology ... #Diagnosis #Differential
Hypernatremia Diagnosis and Workup

Step 1 . Repeat the sodium concentration.
Step 2.  Check plasma osmolality.
NORMAL PLASMA
Hypernatremia Diagnosis ... Repeat the sodium ... Step 2. ... administration Step 3. ... Workup #Algorithm #Nephrology
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
cell epithelial sodium ... of epithelial sodium ... diabetes insipidus ... Defects #Kidney #Nephrology ... #Diagnosis #Differential
Cerebral Salt Wasting vs SIADH - Pathophysiology 
1) Neurological event
2) Sodium loss from tubules
3) Naturiesis →
Neurological event 2) ... Sodium loss from ... tubules 3) Naturiesis ... Pathophysiology #diagnosis #nephrology ... #hyponatremia #