12 results
Hypernatremia Differential Diagnosis Algorithm - Diabetes Insipidus Workup

Step #1 - Consider the history
Step #2 - Assess
Hypernatremia Differential ... history Step #2 ... #Management #Algorithm ... #Sodium #nephrology ... #insipidus #DI
Causes of Hypernatremia - Differential Diagnosis
Inadequate water intake:
 • Lack of access to water
Extrarenal hypotonic fluid
Causes of Hypernatremia ... • Nephrogenic ... diabetes insipidus ... Diagnosis #Causes #nephrology ... #sodium #high
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
renal mechanism 2) ... Euvolemic: Diabetes insipidus ... (central or nephrogenic ... Workup #Algorithm #nephrology ... #sodium
Hypernatremia - Differential Diagnosis and Treatment
Hypernatremia is almost always due to unreplaced water loss (free water
urine osm (in DI ... water unavailable 2) ... : neurogenic, nephrogenic ... Diagnosis #Treatment #management ... #nephrology #sodium
Central vs Nephrogenic Diabetes Insipidus - Desmopressin Challenge
Give desmopressin (intranasal, SQ, IV) and monitor UOsm every
Diabetes Insipidus ... 30 minutes over 2 ... #Diabetes #Insipidus ... #DI #Desmopressin ... Challenge #diagnosis #nephrology
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
cell epithelial sodium ... of epithelial sodium ... diabetes insipidus ... - Vasopressin-2 ... Defects #Kidney #Nephrology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
irrigation • Management ... nephrotic syndrome • Hyponatremia ... and euvolemic hyponatremia ... Excretion #Diuresis #Nephrology ... #Pharmacology #
Primary Polydipsia
Definition: Excessive volitional water intake
Epidemiology:
 • 6-20% of patients with psychiatric disorders - Most commonly
• Symptomatic hyponatremia ... occurs in only 2- ... , Urine Sodium ... Polydipsia #diagnosis #management ... #nephrology
Hyponatremia - Diagnosis and Treatment
Hyponatremia is usually caused by the inability to excrete water normally.
Hyponatremia - Diagnosis ... and Treatment Hyponatremia ... 2) Is ADH elevated ... Diagnosis #Treatment #management ... #nephrology #sodium
SIADH Treatment Options
1. Treat underlying cause of SIADH: Pain, Primary lung pathology, Post-operative phenomenon, Medications, Basically
Basically anything 2. ... promoting passive sodium ... SatyaPatelMD #SIADH #Management ... #hyponatremia # ... nephrology #treatment