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differential causes nephrology comparison management shock acidosis algorithm epithelial high hypertension hyponatremia inherited inopressors kidney lactate lactic pharmacology polydipsia primary
Causes of Hypernatremia - Differential Diagnosis Inadequate water intake: • Lack of access to water Extrarenal hypotonic fluid
Causes of Hypernatremia ... - Differential Diagnosis ... concentrating defect ... insipidus • Nephrogenic ... Causes #nephrology #sodium
Hypernatremia - Differential Diagnosis Workup Algorithm 1) Check Urine Osmolality: > 600 mOsm/kg - Implies extrarenal mechanism
Differential Diagnosis ... Workup Algorithm ... #Differential #Diagnosis ... #Workup #Algorithm ... #nephrology #sodium
Shock and Vasoactive Drugs 1) Determine type and etiology of shock • Distributive: Sepsis, Anaphylaxis, Neurogenic
and Vasoactive Drugs ... , Anaphylaxis, Neurogenic ... Disease, Mechanical Defect ... #inopressors #diagnosis ... management #comparison #table
Etiologies of Hypernatremia - Differential Diagnosis GI losses / Insensible losses Sodium Overload Transcellular Movement of Water Central Diabetes Insipidus
Etiologies of Hypernatremia ... - Differential Diagnosis ... Insensible losses Sodium ... #Differential #Diagnosis ... #Table #Causes
Inherited Defects in Kidney Tubule Epithelial Cells Renal glucosuria - Na+-dependent glucose cotransporter Cystinuria - Amino acid transporter Bartter
Inherited Defects ... cell epithelial sodium ... of epithelial sodium ... Kidney #Nephrology #Diagnosis ... #Differential #Table
Hyponatremia - Differential Diagnosis by Mechanism Decr Blood Pressure (“Decr Effective Circulating Volume”) - Volume depletion
Hyponatremia - Differential ... Diagnosis by Mechanism ... exacerbation) - Drugs ... #Table #Causes ... #Sodium
Shock - Differential Diagnosis Framework MAP = CO x SVR Hypovolemic (↓ Intravascular volume): • Hemorrhage, dehydration due
- Differential Diagnosis ... tone): • Sepsis. neurogenic ... adrenal crisis, drugs ... #table #comparison ... #criticalcare
Causes of Secondary Hypertension - Differential Diagnosis and Screening Testing Common causes: • Renal parenchymal disease
- Differential Diagnosis ... Oral sodium loading ... #Differential #Diagnosis ... Causes #Screening #Workup ... #table
Lactic Acidosis - Differential Diagnosis Framework Type A: Impaired O2 Delivery (DO2) • Decreased O2 Delivery: Hypotension
- Differential Diagnosis ... Beta-Agonists, ↑ work ... Utilization (VO2) • Drugs ... toxic alcohols, Sodium ... #criticalcare #
Primary Polydipsia Definition: Excessive volitional water intake Epidemiology: • 6-20% of patients with psychiatric disorders - Most commonly
• Symptomatic hyponatremia ... dysfunction - K+ deficits ... intoxication Initial Workup ... Urine Osm, Serum Sodium ... , Urine Sodium
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