18 results
Hypernatremia Diagnosis and Workup

Step 1 . Repeat the sodium concentration.
Step 2.  Check plasma osmolality.
NORMAL PLASMA
Hypernatremia Diagnosis ... Repeat the sodium ... Step 2. ... administration Step 3. ... #Diagnosis #Workup
Hypernatremia Differential Diagnosis Algorithm - Diabetes Insipidus Workup

Step #1 - Consider the history
Step #2 - Assess
Diagnosis Algorithm ... Diabetes Insipidus Workup ... history Step #2 ... Uglucose Step #3 ... #nephrology #insipidus
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
Differential Diagnosis ... Workup Algorithm ... renal mechanism 2) ... #Workup #Algorithm ... #nephrology #sodium
Cerebral Salt Wasting vs SIADH - Pathophysiology 
1) Neurological event
2) Sodium loss from tubules
3) Naturiesis →
Neurological event 2) ... Sodium loss from ... tubules 3) Naturiesis ... Pathophysiology #diagnosis ... #nephrology #hyponatremia
Hyponatremia - Differential Diagnosis by Mechanism
Decr Blood Pressure (“Decr Effective Circulating Volume”) 
 - Volume depletion
depletion - Heart ... exacerbation) - Drugs ... osmostat - Cerebral ... #Table #Causes ... #Sodium
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
Inherited Defects in Kidney ... cell epithelial sodium ... of epithelial sodium ... #Nephrology #Diagnosis ... #Differential #Table
Hypernatremia - Differential Diagnosis and Treatment
Hypernatremia is almost always due to unreplaced water loss (free water
water unavailable 2) ... post-obstructive 3) ... Diabetes Insipidus: neurogenic ... patients at risk for cerebral ... #sodium
Shock and Vasoactive Drugs 
1) Determine type and etiology of shock
 • Distributive: Sepsis, Anaphylaxis, Neurogenic
, Anaphylaxis, Neurogenic ... Acute MI, Acute Heart ... Pulmonary embolism 2) ... Nitroprusside, Nesiritide 3) ... #inopressors #diagnosis
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
Insufficiency, Cerebral ... renal perfusion (Heart ... #differential #diagnosis ... #table #sodium ... #nephrology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
disequilibrium syndrome • Diagnosis ... nephrotic syndrome • Hyponatremia ... and euvolemic hyponatremia ... Excretion #Diuresis #Nephrology ... #Medications #Table