24 results
Hypernatremia Differential Diagnosis Algorithm - Diabetes Insipidus Workup

Step #1 - Consider the history
Step #2 - Assess
Diagnosis Algorithm ... Workup Step ... #1 - Consider the ... history Step #2 ... #nephrology #insipidus
Causes of Hypernatremia - Differential Diagnosis
Inadequate water intake:
 • Lack of access to water
Extrarenal hypotonic fluid
Causes of Hypernatremia ... - Differential Diagnosis ... • Nephrogenic ... #Causes #nephrology ... #sodium #high
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
Workup Algorithm ... 1) Check Urine ... renal mechanism 2) ... Euvolemic: Diabetes insipidus ... #nephrology #sodium
Etiologies of Hypernatremia - Differential Diagnosis
GI losses / Insensible losses
Sodium Overload
Transcellular Movement of Water
Central Diabetes Insipidus
Etiologies of Hypernatremia ... - Differential Diagnosis ... Insensible losses Sodium ... sensitivity in kidneys ... #Table #Causes
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
Inherited Defects in Kidney ... of epithelial sodium ... diabetes insipidus ... #Nephrology #Diagnosis ... #Differential #Table
Hypernatremia Diagnosis and Workup

Step 1 . Repeat the sodium concentration.
Step 2.  Check plasma osmolality.
NORMAL PLASMA
Hypernatremia Diagnosis ... 1 . ... Repeat the sodium ... Step 2. ... #Diagnosis #Workup
Classification of Diabetes Insipidus

Central or neurogenic diabetes insipidus:
 - Congenital - Structural malformations affecting the hypothalamus
mutations in AQP-2 ... uropathy, Metabolic causes ... cell disease, Drugs ... Classification #Types #Nephrology ... #Diagnosis #Differential
Hypernatremia - Differential Diagnosis and Treatment
Hypernatremia is almost always due to unreplaced water loss (free water
water unavailable 2) ... post-obstructive 3) Diabetes Insipidus ... : neurogenic, nephrogenic ... Treatment #management #nephrology ... #sodium
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
disequilibrium syndrome • Diagnosis ... caused by Ca2+ ... and euvolemic hyponatremia ... Excretion #Diuresis #Nephrology ... #Medications #Table
Simplified Approach to Acute Kidney Injury (AKI)
1) IS THIS AN EMERGENCY? 
Is there a dialysis indication
Approach to Acute Kidney ... Injury (AKI) 1) ... 2) HISTORY/PHYSICAL ... obstruction, Nephrotoxic drugs ... #diagnosis #nephrology